Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 11/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 11/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 9/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.45 |
| ▸ | USP2 | O75604 | 4/20 | 0.45 |
| ▸ | TSHR | P16473 | 5/20 | 0.45 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.44 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.44 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.44 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4841560 | 0.89 | CYP3A4 (0.49) | CYP3A4CYP2D6CYP2C9CYP2C19KMT2A | |
| SCHEMBL1488416 | 0.80 | MEN1 (0.50) | CYP3A4CYP2D6CYP2C9CYP2C19KMT2A | |
| SCHEMBL10569014 | 0.79 | CYP3A4 (0.54) | CYP3A4CYP2D6CYP2C9CYP2C19KMT2A | |
| SCHEMBL1488335 | 0.77 | CYP3A4 (0.53) | CYP3A4CYP2D6CYP2C9CYP2C19KMT2A | |
| SCHEMBL1221665 | 0.77 | NPSR1 (0.54) | CYP3A4CYP2D6CYP2C9CYP2C19KMT2A | |
| SCHEMBL4833167 | 0.77 | CYP2D6 (0.52) | CYP3A4CYP2D6CYP2C9CYP2C19KMT2A | |
| SCHEMBL4840944 | 0.76 | CYP3A4 (0.46) | CYP3A4CYP2D6CYP2C9CYP2C19KMT2A | |
| SCHEMBL14676735 | 0.76 | CYP3A4 (0.51) | CYP3A4CYP2D6CYP2C9CYP2C19KMT2A | |
| SCHEMBL4782320 | 0.75 | CYP3A4 (0.51) | CYP3A4CYP2D6CYP2C9CYP2C19KMT2A | |
| SCHEMBL1602301 | 0.74 | CYP3A4 (0.57) | CYP3A4CYP2D6CYP2C9CYP2C19KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1592691-A1 | PYRAZOLO[1,5-A][1,3,5]TRIAZINE DERIVATIVES AS CANNABINOID RECEPTOR LIGANDS | Pfizer Products Inc. (US) | 2005-11-09 | — | — | EP | disclosed |
| WO-2004069837-A1 | PYRAZOLO`1,5-A!`1,3,5!TRIAZINE DERIVATIVES AS CANNABINOID RECEPTOR LIGANDS | PFIZER PRODUCTS INC. (US) | 2004-08-19 | — | — | WO | disclosed |