SCHEMBL6206590

SCHEMBL6206590

CC(=O)NCCN(C1CCN([C@@H](C)C(=O)N2CCOCC2)C1=O)S(=O)(=O)c1ccc2cc(Cl)ccc2c1

nearest known ligand 0.79

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
F10 P00742 20/20 0.79

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4495421 1.00 F10 (0.79) F10
SCHEMBL5168675 0.90 F10 (0.82) F10
SCHEMBL5170336 0.89 F10 (0.81) F10
SCHEMBL4482922 0.89 F10 (0.86) F10
SCHEMBL4480278 0.88 F10 (1.00) F10
SCHEMBL5169151 0.88 F10 (0.79) F10
SCHEMBL4481695 0.88 F10 (0.87) F10
Formic Acid SCHEMBL4472155 0.87 F10 (0.78) F10
SCHEMBL6558100 0.87 F10 (0.85) F10
SCHEMBL4467312 0.87 F10 (0.85) F10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1395553-B1 PYRROLIDINE DERIVATIVES AS FACTOR XA INHIBITORS GLAXO GROUP LTD (GB) 2005-02-16 EP claimed