Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 7/20 | 0.35 |
| ▸ | MGAM | O43451 | 4/20 | 0.35 |
| ▸ | GLA | P06280 | 4/20 | 0.35 |
| ▸ | AGL | P35573 | 3/20 | 0.35 |
| ▸ | SI | P14410 | 3/20 | 0.35 |
| ▸ | PYGL | P06737 | 2/20 | 0.35 |
| ▸ | MAN1B1 | Q9UKM7 | 1/20 | 0.35 |
| ▸ | FUCA1 | P04066 | 4/20 | 0.34 |
| ▸ | GBA2 | Q9HCG7 | 3/20 | 0.34 |
| ▸ | GBA1 | P04062 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | LCT | P09848 | 2/20 | 0.34 |
| ▸ | GBA3 | Q9H227 | 2/20 | 0.34 |
| ▸ | MAN2B1 | O00754 | 1/20 | 0.34 |
| ▸ | MAN2B2 | Q9Y2E5 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | TREH | O43280 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6206711 | 1.00 | GAA (0.35) | GAAMGAMGLAAGLSI | |
| SCHEMBL6206710 | 1.00 | GAA (0.35) | GAAMGAMGLAAGLSI | |
| SCHEMBL5240397 | 0.63 | — | — | |
| SCHEMBL14879909 | 0.61 | ESR2 (0.31) | — | |
| SCHEMBL901128 | 0.61 | ESR2 (0.31) | — | |
| SCHEMBL899487 | 0.61 | ESR1 (0.30) | — | |
| Ammonia Solution, Strong SCHEMBL28327714 | 0.60 | — | — | |
| SCHEMBL7911350 | 0.57 | — | — | |
| SCHEMBL7911348 | 0.57 | — | — | |
| SCHEMBL28047878 | 0.56 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1580187-A1 | Apoptogenic and antiproliferative analogs of ceramide | Deigner, Hans-Peter (DE) | 2005-09-28 | — | — | EP | claimed |
| EP-1580187-A1 | Apoptogenic and antiproliferative analogs of ceramide | Deigner, Hans-Peter (DE) | 2005-09-28 | — | — | EP | disclosed |