SCHEMBL6206761

SCHEMBL6206761

CC(=O)NC[C@H]1CN(c2ccc(N3CCC(C(C)C#N)CC3)c(F)c2)C(=O)O1

nearest known ligand 0.70

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MAOB P27338 7/20 0.70
MAOA P21397 5/20 0.70
PTGS1 P23219 2/20 0.70
SDHA P31040 2/20 0.70
LMNA P02545 1/20 0.70
CALML3 P27482 1/20 0.70
F10 P00742 7/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6206760 1.00 MAOB (0.70) MAOBMAOAPTGS1SDHALMNA
SCHEMBL6188560 0.92 MAOB (0.71) MAOBMAOAPTGS1SDHALMNA
SCHEMBL6804192 0.92 MAOB (0.71) MAOBMAOAPTGS1SDHALMNA
SCHEMBL6188751 0.92 MAOB (0.70) MAOBMAOAPTGS1SDHALMNA
SCHEMBL6188755 0.92 MAOB (0.70) MAOBMAOAPTGS1SDHALMNA
SCHEMBL5105329 0.90 MAOB (0.68) MAOBMAOAPTGS1SDHALMNA
SCHEMBL5105331 0.90 MAOB (0.68) MAOBMAOAPTGS1SDHALMNA
SCHEMBL6188369 0.90 MAOB (0.68) MAOBMAOAPTGS1SDHALMNA
SCHEMBL6188370 0.90 MAOB (0.68) MAOBMAOAPTGS1SDHALMNA
SCHEMBL14145200 0.89 MAOB (0.66) MAOBMAOAPTGS1SDHALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1546140-A2 ANTIMICROBIAL OXAZOLIDINONES, PROCESS OF THEIR PREPARATION, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM Wockhardt Limited (IN) 2005-06-29 EP claimed
US-20040235900-A1 Antimicrobial oxazolifinones with improved pharmacokinetic profile and safety advantages WOCKHARDT LIMITED (IN) 2004-11-25 US claimed
WO-2004007488-A2 ANTIMICROBIAL OXAZOLIDINONES, PROCESS OF THEIR PREPARATION, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM WOCKHARDT LIMITED (IN) 2004-01-22 WO claimed
EP-1546140-A2 ANTIMICROBIAL OXAZOLIDINONES, PROCESS OF THEIR PREPARATION, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM Wockhardt Limited (IN) 2005-06-29 EP disclosed
US-20040235900-A1 Antimicrobial oxazolifinones with improved pharmacokinetic profile and safety advantages WOCKHARDT LIMITED (IN) 2004-11-25 US disclosed
WO-2004007488-A2 ANTIMICROBIAL OXAZOLIDINONES, PROCESS OF THEIR PREPARATION, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM WOCKHARDT LIMITED (IN) 2004-01-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040235900-A1 Antimicrobial oxazolifinones with improved pharmacokinetic profile and safety advantages OXA1L, VIP, CYP51A1 MAOB 1589/4885MAOA 2006/4885PTGS1 2160/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.