Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.68 |
| ▸ | MAPT | P10636 | 2/20 | 0.68 |
| ▸ | RAB9A | P51151 | 2/20 | 0.68 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.60 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | GFER | P55789 | 1/20 | 0.53 |
| ▸ | DRD3 | P35462 | 8/20 | 0.50 |
| ▸ | DRD2 | P14416 | 6/20 | 0.50 |
| ▸ | DRD4 | P21917 | 4/20 | 0.50 |
| ▸ | DRD1 | P21728 | 2/20 | 0.50 |
| ▸ | HTR1A | P08908 | 2/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5703655 | 0.98 | MAPT (0.70) | NPC1MAPTRAB9ALOXL2TP53 | |
| SCHEMBL5693569 | 0.93 | MAPT (0.72) | NPC1MAPTRAB9ALOXL2TP53 | |
| SCHEMBL11399187 | 0.89 | MAPT (0.84) | NPC1MAPTRAB9ALOXL2TP53 | |
| SCHEMBL2123399 | 0.86 | MAPT (0.78) | NPC1MAPTRAB9ALOXL2TP53 | |
| SCHEMBL31276791 | 0.86 | MAPT (0.78) | NPC1MAPTRAB9ALOXL2TP53 | |
| SCHEMBL9642061 | 0.86 | MAPT (0.84) | NPC1MAPTRAB9ALOXL2TP53 | |
| SCHEMBL7793708 | 0.83 | MAPT (0.68) | NPC1MAPTRAB9ALOXL2TP53 | |
| SCHEMBL2567453 | 0.83 | MAPT (0.68) | NPC1MAPTRAB9ALOXL2TP53 | |
| SCHEMBL11623669 | 0.83 | MAPT (0.68) | NPC1MAPTRAB9ALOXL2TP53 | |
| SCHEMBL3030438 | 0.83 | NPC1 (0.68) | NPC1MAPTRAB9ALOXL2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1515726-A1 | MORPHOLINE AND TETRAHYDROPYRAN DERIVATIVES AND THEIR USE AS CATHEPSIN INHIBITORS | Aventis Pharmaceuticals, Inc. (US) | 2005-03-23 | — | — | EP | disclosed |
| WO-2004002491-A1 | MORPHOLINE AND TETRAHYDROPYRAN DRIVATIVES AND THEIR USE AS CATHEPSIN INHIBITORS | AVENTIS PHARMACEUTICALS INC. (US) | 2004-01-08 | — | — | WO | disclosed |
| EP-0854388-B1 | Negative-type image recording materials | FUJI PHOTO FILM CO LTD (JP) | 2003-08-13 | — | — | EP | disclosed |
| US-6068963-A | CONTAINS (A) A POLYMER HAVING A HETEROCYCLIC GROUP CONTAINING AN UNSATURATED BOND THEREIN, (B) A CROSS-LINKING AGENT THAT CROSS-LINKS WITH THE AID OF AN ACID, AND (C) A COMPOUND THAT GENERATES AN ACID UPON EXPOSURE TO LIGHT OR HEAT. | FUJI PHOTO FILM CO., LTD. (JP) | 2000-05-30 | — | — | US | disclosed |
| EP-0949238-A1 | SUBSTITUTED PROPIONYL DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1999-10-13 | — | — | EP | disclosed |
| EP-0854388-A2 | Negative-type image recording materials | FUJI PHOTO FILM CO., LTD. (JP) | 1998-07-22 | — | — | EP | disclosed |