Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 2/20 | 0.38 |
| ▸ | CASP6 | P55212 | 1/20 | 0.38 |
| ▸ | CDK1 | P06493 | 2/20 | 0.33 |
| ▸ | CDK2 | P24941 | 2/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
| ▸ | BPTF | Q12830 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6206887 | 1.00 | GFER (0.38) | GFERCASP6CDK1CDK2MCHR1 | |
| SCHEMBL6206883 | 1.00 | GFER (0.38) | GFERCASP6CDK1CDK2MCHR1 | |
| SCHEMBL1749320 | 0.91 | GFER (0.44) | GFERCASP6CDK1CDK2MCHR1 | |
| SCHEMBL6206886 | 0.88 | GFER (0.34) | GFERCASP6CDK1CDK2KDM4E | |
| SCHEMBL1749111 | 0.76 | MAPT (0.41) | GFERCASP6CDK1CDK2KDM4E | |
| SCHEMBL1749109 | 0.76 | MAPT (0.41) | GFERCASP6CDK1CDK2KDM4E | |
| SCHEMBL1749110 | 0.76 | MAPT (0.41) | GFERCASP6CDK1CDK2KDM4E | |
| SCHEMBL1749513 | 0.75 | GFER (0.49) | GFERCASP6MCHR1KDM4EALDH1A1 | |
| SCHEMBL1749166 | 0.74 | GBA1 (0.44) | GAA | |
| SCHEMBL1749164 | 0.74 | GBA1 (0.44) | GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1597228-A2 | SUBSTITUTED N-ARYLHETEROCYCLES, METHOD FOR PRODUCTION AND USE THEREOF AS MEDICAMENTS | Sanofi-Aventis Deutschland GmbH (DE) | 2005-11-23 | — | — | EP | disclosed |
| WO-2004072025-A2 | SUBSTITUTED N-ARYLHETEROCYCLES, METHOD FOR PRODUCTION AND USE THEREOF AS MEDICAMENTS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2004-08-26 | — | — | WO | disclosed |