Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GALR1 | P47211 | 5/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | GALR2 | O43603 | 5/20 | 0.41 |
| ▸ | CRHR1 | P34998 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CDK4 | P11802 | 2/20 | 0.39 |
| ▸ | CCND1 | P24385 | 2/20 | 0.39 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.39 |
| ▸ | CCND3 | P30281 | 1/20 | 0.39 |
| ▸ | CDK9 | P50750 | 1/20 | 0.39 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CDK1 | P06493 | 2/20 | 0.37 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.37 |
| ▸ | CDK2 | P24941 | 2/20 | 0.37 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.37 |
| ▸ | AGPAT2 | O15120 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6235647 | 0.85 | GALR1 (0.47) | GALR1L3MBTL1CYP2D6CYP2C19GALR2 | |
| SCHEMBL5549889 | 0.83 | GALR1 (0.45) | GALR1L3MBTL1CYP2D6CYP2C19GALR2 | |
| SCHEMBL6208381 | 0.82 | GALR1 (0.47) | GALR1L3MBTL1CYP2D6CYP2C19GALR2 | |
| SCHEMBL5550587 | 0.81 | GALR1 (0.48) | GALR1L3MBTL1CYP2D6CYP2C19GALR2 | |
| SCHEMBL6429951 | 0.80 | GALR1 (0.42) | GALR1L3MBTL1CYP2D6CYP2C19GALR2 | |
| SCHEMBL6429322 | 0.80 | GALR1 (0.47) | GALR1L3MBTL1CYP2D6CYP2C19GALR2 | |
| SCHEMBL6428131 | 0.79 | GALR1 (0.46) | GALR1L3MBTL1CYP2D6CYP2C19GALR2 | |
| SCHEMBL4838923 | 0.78 | GALR1 (0.67) | GALR1L3MBTL1CYP2D6CYP2C19GALR2 | |
| SCHEMBL5549892 | 0.77 | GALR1 (0.44) | GALR1L3MBTL1CYP2D6CYP2C19GALR2 | |
| SCHEMBL5553491 | 0.77 | GALR1 (0.46) | GALR1GALR2CDK4CCND1PIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1560817-A1 | METHODS AND COMPOSITIONS OF NOVEL TRIAZINE COMPOUNDS | Reddy US Therapeutics, Inc. (US) | 2005-08-10 | — | — | EP | claimed |
| WO-2004026844-A9 | METHODS AND COMPOSITIONS OF NOVEL TRIAZINE COMPOUNDS | REDDY US THERAPEUTICS INC (US) | 2004-11-11 | — | — | WO | claimed |
| WO-2004026844-A1 | METHODS AND COMPOSITIONS OF NOVEL TRIAZINE COMPOUNDS | REDDY US THERAPEUTICS, INC. (US) | 2004-04-01 | — | — | WO | claimed |