Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 14/20 | 0.46 |
| ▸ | CDK1 | P06493 | 1/20 | 0.46 |
| ▸ | CDK2 | P24941 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.39 |
| ▸ | GSK3A | P49840 | 1/20 | 0.38 |
| ▸ | PRKAB2 | O43741 | 2/20 | 0.35 |
| ▸ | PRKAG1 | P54619 | 2/20 | 0.35 |
| ▸ | PRKAA2 | P54646 | 2/20 | 0.35 |
| ▸ | PRKAA1 | Q13131 | 2/20 | 0.35 |
| ▸ | PRKAG3 | Q9UGI9 | 2/20 | 0.35 |
| ▸ | PRKAG2 | Q9UGJ0 | 2/20 | 0.35 |
| ▸ | PRKAB1 | Q9Y478 | 2/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 2/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | SMYD2 | Q9NRG4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6207558 | 0.84 | GSK3B (0.58) | GSK3BCDK1CDK2CYP1A2GSK3A | |
| SCHEMBL4500932 | 0.81 | GSK3B (0.62) | GSK3BCDK1CDK2CYP1A2GSK3A | |
| SCHEMBL4492373 | 0.76 | GSK3B (0.70) | GSK3BCDK1CDK2CYP1A2PRKAB2 | |
| SCHEMBL4494753 | 0.76 | GSK3B (0.64) | GSK3BCDK1CDK2CYP1A2GSK3A | |
| SCHEMBL1461200 | 0.75 | GSK3B (0.61) | GSK3BCDK1CDK2CYP1A2PRKAB2 | |
| SCHEMBL1461071 | 0.70 | GSK3B (0.52) | GSK3BCDK1CDK2CYP1A2ACHE | |
| SCHEMBL1461084 | 0.69 | GSK3B (0.66) | GSK3BCDK1CDK2CYP1A2PRKAB2 | |
| SCHEMBL4492707 | 0.68 | GSK3B (0.69) | GSK3BCDK1CDK2CYP1A2PRKAB2 | |
| SCHEMBL4497559 | 0.68 | GSK3B (0.74) | GSK3BCDK1CDK2CYP1A2PRKAB2 | |
| SCHEMBL4499482 | 0.66 | GSK3B (0.75) | GSK3BCDK1CDK2CYP1A2GSK3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1537087-A1 | NOVEL AMINOINDAZOLE DERIVATIVES AS MEDICINES AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | Aventis Pharma S.A. (FR) | 2005-06-08 | — | — | EP | disclosed |
| WO-2004022544-A1 | NOVEL AMINOINDAZOLE DERIVATIVES AS MEDICINES AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | AVENTIS PHARMA S.A. (FR) | 2004-03-18 | — | — | WO | disclosed |