Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 13/20 | 0.41 |
| ▸ | PPARA | Q07869 | 14/20 | 0.40 |
| ▸ | PPARG | P37231 | 5/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.38 |
| ▸ | NQO2 | P16083 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1401199 | 0.86 | PPARD (0.60) | PPARDPPARAPPARG | |
| SCHEMBL1401197 | 0.86 | PPARD (0.60) | PPARDPPARAPPARG | |
| SCHEMBL1401034 | 0.84 | PPARA (0.57) | PPARAPPARG | |
| SCHEMBL12798881 | 0.84 | PPARA (0.48) | PPARDPPARAPPARG | |
| SCHEMBL1400440 | 0.80 | PPARA (0.55) | PPARDPPARAPPARG | |
| SCHEMBL1401035 | 0.79 | PPARD (0.61) | PPARDPPARA | |
| SCHEMBL1400419 | 0.79 | PPARA (0.56) | PPARDPPARAPPARG | |
| SCHEMBL1400752 | 0.79 | PPARD (0.59) | PPARDPPARAPPARG | |
| SCHEMBL3119829 | 0.78 | PPARD (0.56) | PPARDPPARA | |
| SCHEMBL1400562 | 0.76 | PPARA (0.56) | PPARDPPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1578715-A2 | INDANE ACETIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICAL AGENTS, INTERMEDIATES, AND METHOD OF PREPARATION | Bayer Pharmaceuticals Corporation (US) | 2005-09-28 | — | — | EP | disclosed |
| WO-2004058174-A2 | INDANE ACETIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICAL AGENTS, INTERMEDIATES, AND METHOD OF PREPARATION | BAYER PHARMACEUTICALS CORPORATION (US) | 2004-07-15 | — | — | WO | disclosed |