Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 18/20 | 0.39 |
| ▸ | CNR2 | P34972 | 15/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4842366 | 0.93 | CNR1 (0.45) | CNR1CNR2TDP1MEN1NPC1 | |
| SCHEMBL4840867 | 0.91 | CNR1 (0.47) | CNR1CNR2 | |
| SCHEMBL4836443 | 0.85 | CNR1 (0.43) | CNR1CNR2 | |
| SCHEMBL4842175 | 0.85 | CNR1 (0.55) | CNR1CNR2 | |
| SCHEMBL5386529 | 0.80 | CNR1 (0.45) | CNR1CNR2TDP1MEN1NPC1 | |
| SCHEMBL1317852 | 0.80 | CNR1 (0.44) | CNR1CNR2 | |
| SCHEMBL4841187 | 0.79 | CNR1 (0.64) | CNR1CNR2 | |
| SCHEMBL5396499 | 0.78 | CNR1 (0.45) | CNR1CNR2TDP1MEN1NPC1 | |
| SCHEMBL27633550 | 0.78 | CNR1 (0.34) | CNR1CNR2MEN1NPC1RAB9A | |
| SCHEMBL4842601 | 0.74 | SRC (0.41) | CNR1CNR2MEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1592691-A1 | PYRAZOLO[1,5-A][1,3,5]TRIAZINE DERIVATIVES AS CANNABINOID RECEPTOR LIGANDS | Pfizer Products Inc. (US) | 2005-11-09 | — | — | EP | disclosed |
| WO-2004069837-A1 | PYRAZOLO`1,5-A!`1,3,5!TRIAZINE DERIVATIVES AS CANNABINOID RECEPTOR LIGANDS | PFIZER PRODUCTS INC. (US) | 2004-08-19 | — | — | WO | disclosed |