Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K4 | P45985 | 1/20 | 0.49 |
| ▸ | CDC7 | O00311 | 1/20 | 0.47 |
| ▸ | GSK3B | P49841 | 5/20 | 0.46 |
| ▸ | CDK1 | P06493 | 1/20 | 0.46 |
| ▸ | CDK2 | P24941 | 1/20 | 0.46 |
| ▸ | PRKAB2 | O43741 | 2/20 | 0.46 |
| ▸ | PRKAG1 | P54619 | 2/20 | 0.46 |
| ▸ | PRKAA2 | P54646 | 2/20 | 0.46 |
| ▸ | PRKAA1 | Q13131 | 2/20 | 0.46 |
| ▸ | PRKAG3 | Q9UGI9 | 2/20 | 0.46 |
| ▸ | PRKAG2 | Q9UGJ0 | 2/20 | 0.46 |
| ▸ | PRKAB1 | Q9Y478 | 2/20 | 0.46 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.43 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.41 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.41 |
| ▸ | USP1 | O94782 | 1/20 | 0.40 |
| ▸ | WDR48 | Q8TAF3 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CCNC | P24863 | 1/20 | 0.39 |
| ▸ | CDK8 | P49336 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL1461210 | 0.98 | CDC7 (0.48) | MAP2K4CDC7GSK3BCDK1CDK2 | |
| SCHEMBL4498891 | 0.89 | MAP2K4 (0.57) | MAP2K4CDC7GSK3BCDK1CDK2 | |
| SCHEMBL4497411 | 0.88 | GSK3B (0.53) | CDC7GSK3BCDK1CDK2PRKAB2 | |
| SCHEMBL1378107 | 0.85 | GSK3B (0.49) | MAP2K4CDC7GSK3BCDK1CDK2 | |
| SCHEMBL4495395 | 0.84 | GSK3B (0.52) | MAP2K4CDC7GSK3BCDK1CDK2 | |
| SCHEMBL4502817 | 0.82 | MAPK8 (0.51) | MAP2K4CDC7GSK3BCDK1CDK2 | |
| SCHEMBL4494733 | 0.82 | GSK3B (0.55) | GSK3BCDK1CDK2PRKAB2PRKAG1 | |
| SCHEMBL4492720 | 0.81 | GSK3B (0.53) | CDC7GSK3BCDK1CDK2PRKAB2 | |
| SCHEMBL4500596 | 0.79 | GSK3B (0.53) | MAP2K4GSK3BCDK1CDK2PRKAB2 | |
| SCHEMBL4492484 | 0.79 | GSK3B (0.58) | MAP2K4CDC7GSK3BCDK1CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1537087-A1 | NOVEL AMINOINDAZOLE DERIVATIVES AS MEDICINES AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | Aventis Pharma S.A. (FR) | 2005-06-08 | — | — | EP | disclosed |
| WO-2004022544-A1 | NOVEL AMINOINDAZOLE DERIVATIVES AS MEDICINES AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | AVENTIS PHARMA S.A. (FR) | 2004-03-18 | — | — | WO | disclosed |