SCHEMBL6207723

SCHEMBL6207723

CCCOc1cc(-c2nc3c(s2)CCCC3)ccc1OCCCOc1ccc2c(c1)CC[C@@H]2OC(C)=O

nearest known ligand 0.66

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PPARD Q03181 20/20 0.66
PPARA Q07869 20/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6207729 0.91 PPARD (0.63) PPARDPPARA
SCHEMBL1400437 0.86 PPARD (0.87) PPARDPPARA
SCHEMBL1400416 0.84 PPARA (0.65) PPARDPPARA
SCHEMBL12798741 0.84 PPARD (0.74) PPARDPPARA
SCHEMBL1400648 0.82 PPARD (0.87) PPARDPPARA
SCHEMBL1400681 0.79 PPARD (1.00) PPARDPPARA
SCHEMBL12798738 0.79 PPARD (0.84) PPARDPPARA
SCHEMBL13323921 0.79 PPARD (0.93) PPARDPPARA
SCHEMBL1400380 0.79 PPARA (0.74) PPARDPPARA
SCHEMBL26883085 0.78 PPARD (0.65) PPARDPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1578715-A2 INDANE ACETIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICAL AGENTS, INTERMEDIATES, AND METHOD OF PREPARATION Bayer Pharmaceuticals Corporation (US) 2005-09-28 EP disclosed
WO-2004058174-A2 INDANE ACETIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICAL AGENTS, INTERMEDIATES, AND METHOD OF PREPARATION BAYER PHARMACEUTICALS CORPORATION (US) 2004-07-15 WO disclosed