Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 3/20 | 0.46 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.44 |
| ▸ | MRGPRX4 | Q96LA9 | 5/20 | 0.44 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.40 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.40 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.40 |
| ▸ | XDH | P47989 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6206807 | 1.00 | NR4A2 (0.46) | NR4A2SMPD1MRGPRX4MAP4K4NPC1 | |
| SCHEMBL6207845 | 1.00 | NR4A2 (0.46) | NR4A2SMPD1MRGPRX4MAP4K4NPC1 | |
| SCHEMBL6206165 | 0.88 | SPHK2 (0.50) | NR4A2SMPD1MRGPRX4NPC1RAB9A | |
| SCHEMBL6206166 | 0.88 | SPHK2 (0.50) | NR4A2SMPD1MRGPRX4NPC1RAB9A | |
| SCHEMBL6206160 | 0.88 | SPHK2 (0.50) | NR4A2SMPD1MRGPRX4NPC1RAB9A | |
| SCHEMBL6204954 | 0.86 | MRGPRX4 (0.42) | NR4A2SMPD1MRGPRX4NPC1RAB9A | |
| SCHEMBL6204951 | 0.86 | MRGPRX4 (0.42) | NR4A2SMPD1MRGPRX4NPC1RAB9A | |
| SCHEMBL6204958 | 0.86 | MRGPRX4 (0.42) | NR4A2SMPD1MRGPRX4NPC1RAB9A | |
| SCHEMBL6205448 | 0.80 | NR4A2 (0.46) | NR4A2MRGPRX4NPC1RAB9ASPHK2 | |
| SCHEMBL6205447 | 0.80 | NR4A2 (0.46) | NR4A2MRGPRX4NPC1RAB9ASPHK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100763-B1 | DIKETOACID-DERIVATIVES AS INHIBITORS OF POLYMERASES | ANGELETTI P IST RICHERCHE BIO (IT) | 2005-06-22 | — | — | EP | claimed |