Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.55 |
| ▸ | RPA1 | P27694 | 6/20 | 0.54 |
| ▸ | MALT1 | Q9UDY8 | 2/20 | 0.51 |
| ▸ | MARS1 | P56192 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | BCL2 | P10415 | 1/20 | 0.46 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5148814 | 0.99 | CHRNA7 (0.54) | CHRNA7RPA1MALT1MARS1PTGS2 | |
| SCHEMBL14504509 | 0.92 | CHRNA7 (0.53) | CHRNA7RPA1MALT1MARS1PTGS2 | |
| SCHEMBL14504637 | 0.89 | RPA1 (0.53) | CHRNA7RPA1MALT1MARS1PTGS2 | |
| SCHEMBL3817516 | 0.88 | CHRNA7 (0.53) | CHRNA7RPA1MALT1MARS1PTGS2 | |
| SCHEMBL5148847 | 0.88 | RPA1 (0.55) | CHRNA7RPA1MALT1MARS1PTGS2 | |
| SCHEMBL5418312 | 0.86 | RPA1 (0.58) | CHRNA7RPA1MALT1MARS1PTGS2 | |
| SCHEMBL14504643 | 0.86 | RPA1 (0.54) | CHRNA7RPA1MALT1MARS1PTGS2 | |
| Hydrochloric Acid SCHEMBL5151848 | 0.85 | MALT1 (0.43) | CHRNA7RPA1MALT1BCL2MDM2 | |
| SCHEMBL5147822 | 0.85 | CHRNA7 (0.52) | CHRNA7RPA1MALT1MARS1PTGS2 | |
| Methane SCHEMBL5147829 | 0.85 | RPA1 (0.48) | CHRNA7RPA1MALT1MARS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1567503-A1 | PYRAZOLE DERIVATIVES USEFUL AS COX-I INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-08-31 | — | — | EP | disclosed |
| WO-2004050632-A1 | PYRAZOLE DERIVATIVES USEFUL AS COX-I INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-06-17 | — | — | WO | disclosed |