SCHEMBL6208036

SCHEMBL6208036

CC(=O)O[C@H]1CCc2cc(OCCCN(C)c3nc(Cl)ncc3Cl)ccc21

nearest known ligand 0.50

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PPARD Q03181 20/20 0.50
PPARA Q07869 17/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3008804 0.84 PPARD (0.69) PPARDPPARA
SCHEMBL1400883 0.81 PPARA (0.55) PPARA
SCHEMBL12798958 0.81 PPARD (0.59) PPARDPPARA
SCHEMBL3008260 0.77 PPARD (0.79) PPARDPPARA
SCHEMBL12798931 0.75 PPARD (0.68) PPARDPPARA
SCHEMBL1400465 0.74 PPARA (0.58) PPARDPPARA
SCHEMBL12849435 0.74 PPARD (0.64) PPARDPPARA
SCHEMBL1400525 0.73 PPARD (0.74) PPARDPPARA
SCHEMBL1400616 0.73 PPARA (0.74) PPARDPPARA
SCHEMBL1400961 0.73 PPARD (0.73) PPARDPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1578715-A2 INDANE ACETIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICAL AGENTS, INTERMEDIATES, AND METHOD OF PREPARATION Bayer Pharmaceuticals Corporation (US) 2005-09-28 EP disclosed
WO-2004058174-A2 INDANE ACETIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICAL AGENTS, INTERMEDIATES, AND METHOD OF PREPARATION BAYER PHARMACEUTICALS CORPORATION (US) 2004-07-15 WO disclosed