Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 16/20 | 0.40 |
| ▸ | PPARD | Q03181 | 8/20 | 0.40 |
| ▸ | PPARG | P37231 | 12/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1400726 | 0.84 | PPARA (0.54) | PPARAPPARG | |
| SCHEMBL20214772 | 0.75 | PPARD (0.55) | PPARAPPARDPPARG | |
| SCHEMBL1400503 | 0.74 | PPARA (0.57) | PPARAPPARDPPARG | |
| SCHEMBL6206461 | 0.72 | PPARD (0.48) | PPARAPPARDPPARG | |
| SCHEMBL3025877 | 0.70 | PPARD (0.62) | PPARAPPARD | |
| SCHEMBL6208241 | 0.69 | PPARA (0.49) | PPARAPPARDPPARG | |
| SCHEMBL4684227 | 0.69 | PPARA (0.61) | PPARAPPARDPPARG | |
| SCHEMBL4679810 | 0.68 | PPARA (0.61) | PPARAPPARDPPARG | |
| SCHEMBL1400727 | 0.68 | PPARA (0.54) | PPARAPPARG | |
| SCHEMBL6207572 | 0.68 | PPARD (0.52) | PPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1578715-A2 | INDANE ACETIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICAL AGENTS, INTERMEDIATES, AND METHOD OF PREPARATION | Bayer Pharmaceuticals Corporation (US) | 2005-09-28 | — | — | EP | disclosed |
| WO-2004058174-A2 | INDANE ACETIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICAL AGENTS, INTERMEDIATES, AND METHOD OF PREPARATION | BAYER PHARMACEUTICALS CORPORATION (US) | 2004-07-15 | — | — | WO | disclosed |