⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL3998948 | 0.97 | — | — | |
| Iodide SCHEMBL4690067 | 0.95 | — | — | |
| SCHEMBL28193341 | 0.74 | — | — | |
| SCHEMBL21785 | 0.73 | — | — | |
| SCHEMBL21097017 | 0.73 | — | — | |
| SCHEMBL17075221 | 0.73 | — | — | |
| SCHEMBL28904204 | 0.73 | — | — | |
| SCHEMBL11343243 | 0.70 | CRBN (0.31) | — | |
| SCHEMBL11240236 | 0.70 | — | — | |
| Iodide SCHEMBL11727191 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-7247287-A | — | — | None | — | — | JP | disclosed |
| CN-119823119-A | Pol theta inhibitor and preparation method, pharmaceutical composition and application thereof | 中国药科大学 | 2025-04-15 | — | — | CN | disclosed |
| CN-115286625-B | Glutaminase allosteric site covalent inhibitor and preparation method and application thereof | 浙江工业大学 | 2025-03-25 | — | — | CN | disclosed |
| CN-118201921-A | Lactams as CBL-B inhibitors selective for C-CBL | 基因泰克公司 | 2024-06-14 | — | — | CN | disclosed |
| CN-111440199-B | Macrocyclic glutaminase GLS1 inhibitor or pharmaceutically acceptable salt thereof, and preparation method and application thereof | 中国药科大学 | 2023-02-24 | — | — | CN | disclosed |
| CN-115286625-A | Glutaminase allosteric site covalent inhibitor and preparation method and application thereof | 浙江工业大学 | 2022-11-04 | — | — | CN | disclosed |
| CN-111440199-A | Macrocyclic glutaminase G L S1 inhibitor or pharmaceutically acceptable salt thereof, and preparation method and application thereof | 中国药科大学 | 2020-07-24 | — | — | CN | disclosed |
| CN-104177288-B | Semicarbazone derivatives, pharmaceutical compositions and uses thereof | 中国人民解放军军事医学科学院毒物药物研究所 | 2020-05-01 | — | — | CN | disclosed |
| US-20150313883-A1 | HYDROXYBENZOATE SALTS OF METANICOTINE COMPOUNDS | TARGACEPT INC (US) | 2015-11-05 | — | — | US | disclosed |
| US-9107915-B2 | Hydroxybenzoate salts of metanicotine compounds | TARGACEPT, INC. (US) | 2015-08-18 | — | — | US | disclosed |
| US-4513135-A | GAMMA-AMINOBUTYRIC ACID BINDING AGTIVATORS | ELI LILLY AND COMPANY (US) | 1985-04-23 | — | — | US | disclosed |
| US-4425155-A | 1,2,4-TRIAZINES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-01-10 | — | — | US | disclosed |
| US-4423053-A | Derivatives of 2-amino-5-(o-sulphamidophenyl)-1,3,4-thiadiazol as antiviral agents and a process for the preparation thereof | Societa Italo-Britannica L. Manetti-H. Roberts & Co. (IT) | 1983-12-27 | — | — | US | disclosed |
| EP-0088593-A2 | 1,2,4-Triazine and pyrazine derivatives | ELI LILLY AND COMPANY (US) | 1983-09-14 | — | — | EP | disclosed |
| EP-0061434-A1 | Derivatives of 2-amino-5-(o-sulphamidophenyl)-1,3,4-thiadiazole as antiviral agents and a process for the preparation thereof | Società Italo-Britannica L. Manetti - H. Roberts & C. (IT) | 1982-09-29 | — | — | EP | disclosed |
| US-4338248-A | RADIOACTIVE DIAGNOSTIC AGENT | NIHON MEDI-PHYSICS CO., LTD. (JP) | 1982-07-06 | — | — | US | disclosed |
| EP-0024464-B1 | 2-OXOPROPIONALDEHYDE BIS(THIOSEMICARBAZONE)DERIVATIVES AND THEIR PRODUCTION AND USE | NIHON MEDI-PHYSICS CO., LTD. (JP) | 1982-05-12 | — | — | EP | disclosed |
| US-4287362-A | AS CHELATING AGENTS IN COMBINATION WITH PROTEINS AND A RADIOACTIVE ISOTOPE OF TECHNETIUM FOR DIAGNOSIS | NIHON MEDI-PHYSICS CO., LTD. (JP) | 1981-09-01 | — | — | US | disclosed |
| EP-0024464-A1 | 2-Oxopropionaldehyde bis(thiosemicarbazone)derivatives and their production and use | NIHON MEDI-PHYSICS CO., LTD. (JP) | 1981-03-11 | — | — | EP | disclosed |
| US-4132736-A | Preparation of 4-alkylthiosemicarbazides | BAYER AKTIENGESELLSCHAFT (DE) | 1979-01-02 | — | — | US | disclosed |