⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1767791 | 1.00 | — | — | |
| SCHEMBL11946108 | 1.00 | — | — | |
| Iodide SCHEMBL3998952 | 0.97 | — | — | |
| Iodide SCHEMBL5918335 | 0.97 | — | — | |
| Iodide SCHEMBL15808777 | 0.94 | — | — | |
| SCHEMBL999515 | 0.71 | — | — | |
| SCHEMBL15336485 | 0.71 | — | — | |
| SCHEMBL13850734 | 0.71 | — | — | |
| SCHEMBL11624372 | 0.71 | — | — | |
| Iodide SCHEMBL1763607 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-7247287-A | — | — | None | — | — | JP | disclosed |
| CN-119823119-A | Pol theta inhibitor and preparation method, pharmaceutical composition and application thereof | 中国药科大学 | 2025-04-15 | — | — | CN | disclosed |
| CN-115286625-B | Glutaminase allosteric site covalent inhibitor and preparation method and application thereof | 浙江工业大学 | 2025-03-25 | — | — | CN | disclosed |
| WO-2023094594-A1 | SUBSTITUTED DIHYDROPYRANOPYRIDINES, SALTS OR N-OXIDES THEREOF AND THEIR USE AS HERBICIDALLY ACTIVE SUBSTANCES | BAYER AKTIENGESELLSCHAFT (DE) | 2023-06-01 | — | — | WO | disclosed |
| CN-111440199-B | Macrocyclic glutaminase GLS1 inhibitor or pharmaceutically acceptable salt thereof, and preparation method and application thereof | 中国药科大学 | 2023-02-24 | — | — | CN | disclosed |
| CN-115286625-A | Glutaminase allosteric site covalent inhibitor and preparation method and application thereof | 浙江工业大学 | 2022-11-04 | — | — | CN | disclosed |
| CN-111440199-A | Macrocyclic glutaminase G L S1 inhibitor or pharmaceutically acceptable salt thereof, and preparation method and application thereof | 中国药科大学 | 2020-07-24 | — | — | CN | disclosed |
| CN-108467386-A | 1,2,4- triazine -3- the amine derivants of thick heteroaryl substitution, preparation method and its application in medicine | 江苏恒瑞医药股份有限公司 | 2018-08-31 | — | — | CN | disclosed |
| US-9718821-B2 | Pyridopyrimidinone inhibitors of kinases | ABBVIE INC. (US) | 2017-08-01 | — | — | US | disclosed |
| EP-2847174-B1 | PYRIMIDINONE CARBOXAMIDES AS INHIBITORS OF ENDOTHELIAL LIPASE | BRISTOL MYERS SQUIBB CO (US) | 2017-05-17 | — | — | EP | disclosed |
| JP-H07247287-A | OPTICALLY ACTIVE DIHYDROFUROPYRIDINE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION CONTAINING THE SAME | DAINIPPON INK & CHEM INC | 1995-09-26 | — | — | JP | disclosed |
| US-5278133-A | Benzyl pyridones antigrowth agent | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1994-01-11 | — | — | US | disclosed |
| US-5260261-A | Fused pyridine herbicides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-11-09 | — | — | US | disclosed |
| EP-0233804-B1 | MONOARYL-5-AS TRIAZINONES SUBSTITUTED IN POSITION 2, PROCESS FOR THEIR PREPARATION AND THEIR USE AS PHARMACEUTICAL PREPARATIONS | PIERRE FABRE MEDICAMENT (FR) | 1991-09-25 | — | — | EP | disclosed |
| EP-0233804-A1 | Monoaryl-5-as triazinones substituted in position 2, process for their preparation and their use as pharmaceutical preparations | PIERRE FABRE MEDICAMENT (FR) | 1987-08-26 | — | — | EP | disclosed |
| EP-0088593-B1 | 1,2,4-TRIAZINE AND PYRAZINE DERIVATIVES | ELI LILLY AND COMPANY (US) | 1987-05-27 | — | — | EP | disclosed |
| US-4585861-A | ACTIVATORS OF GAMMA-AMINOBUTYRIC ACID AND BENZODIAZEPINE BINDING | ELI LILLY AND COMPANY (US) | 1986-04-29 | — | — | US | disclosed |
| US-4513135-A | GAMMA-AMINOBUTYRIC ACID BINDING AGTIVATORS | ELI LILLY AND COMPANY (US) | 1985-04-23 | — | — | US | disclosed |
| US-4425155-A | 1,2,4-TRIAZINES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-01-10 | — | — | US | disclosed |
| EP-0088593-A2 | 1,2,4-Triazine and pyrazine derivatives | ELI LILLY AND COMPANY (US) | 1983-09-14 | — | — | EP | disclosed |