Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 20/20 | 0.67 |
| ▸ | F2 | P00734 | 3/20 | 0.67 |
| ▸ | KLKB1 | P03952 | 3/20 | 0.67 |
| ▸ | PLAT | P00750 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4471996 | 0.84 | F10 (0.67) | F10F2KLKB1PLAT | |
| SCHEMBL4704227 | 0.83 | F10 (0.71) | F10F2KLKB1PLAT | |
| SCHEMBL24324150 | 0.83 | F10 (0.56) | F10F2KLKB1PLAT | |
| SCHEMBL5936074 | 0.82 | F10 (0.75) | F10F2KLKB1PLAT | |
| SCHEMBL4704211 | 0.82 | F10 (0.70) | F10F2KLKB1PLAT | |
| SCHEMBL4702044 | 0.82 | F10 (0.70) | F10F2KLKB1PLAT | |
| SCHEMBL4702481 | 0.82 | F10 (0.75) | F10F2KLKB1PLAT | |
| SCHEMBL4704212 | 0.81 | F10 (0.66) | F10F2KLKB1PLAT | |
| SCHEMBL4704197 | 0.81 | F10 (1.00) | F10F2KLKB1PLAT | |
| SCHEMBL23752209 | 0.81 | F10 (1.00) | F10F2KLKB1PLAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1567489-A1 | PYRROLIDIN-2-ONE DERIVATIVES AS INHIBITORS OF THROMBIN AND FACTOR XA | GLAXO GROUP LIMITED (GB) | 2005-08-31 | — | — | EP | disclosed |
| WO-2004052851-A1 | PYRROLYDIN-2-ONE DERIVATIVES AS INHIBITORS OF THROMBIN AND FACTOR XA | GLAXO GROUP LIMITED (GB) | 2004-06-24 | — | — | WO | disclosed |