Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 2/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | PTGES | O14684 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6208551 | 0.91 | NR1H2 (0.36) | PDE2APDE10AATMNR1H2NR1H3 | |
| SCHEMBL6209661 | 0.82 | PDE2A (0.37) | PDE2APDE10AATMHTTLMNA | |
| SCHEMBL5202844 | 0.80 | PDE2A (0.35) | PDE2APDE10AHTTLMNAMAPK1 | |
| SCHEMBL5202950 | 0.80 | HTT (0.36) | PDE2APDE10AATMHTTLMNA | |
| SCHEMBL6976749 | 0.80 | PDE2A (0.35) | PDE2APDE10AHTTLMNAMAPK1 | |
| SCHEMBL7527087 | 0.80 | PDE2A (0.35) | PDE2APDE10AHTTLMNAMAPK1 | |
| SCHEMBL6972041 | 0.78 | PDE2A (0.34) | PDE2APDE10AATMHTTLMNA | |
| SCHEMBL7526323 | 0.78 | PDE2A (0.34) | PDE2APDE10AHTTLMNAMAPK1 | |
| SCHEMBL2933280 | 0.78 | PDE2A (0.34) | PDE2APDE10AATMHTTLMNA | |
| SCHEMBL5726642 | 0.77 | PDE2A (0.33) | PDE2APDE10AHTTLMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1124827-B1 | 3-(SUBSTITUTED PHENYL)-5-(SUBSTITUTED HETEROCYCLYL)-1,2,4-TRIAZOLE COMPOUNDS | DOW AGROSCIENCES LLC (US) | 2005-11-30 | — | — | EP | disclosed |
| US-6413997-B1 | INSECTICIDES, MITICIDES | DOW AGROSCIENCES LLC | 2002-07-02 | — | — | US | disclosed |