Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | HTR2C | P28335 | 2/20 | 0.39 |
| ▸ | HTR2B | P41595 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18029724 | 0.74 | HTR2A (0.39) | HTR2AHTR2CHTR2B | |
| SCHEMBL18007628 | 0.74 | HTR2A (0.39) | HTR2AHTR2CHTR2B | |
| SCHEMBL21586422 | 0.71 | HTR2A (0.37) | HTR2AHTR2CHTR2B | |
| SCHEMBL19869245 | 0.70 | HTR2A (0.43) | HTR2AHTR2CHTR2B | |
| SCHEMBL338146 | 0.68 | HTR2A (0.35) | HTR2AHTR2CHTR2B | |
| SCHEMBL21962060 | 0.67 | — | — | |
| SCHEMBL9465522 | 0.64 | — | — | |
| SCHEMBL3337706 | 0.62 | HTR2A (0.31) | HTR2AHTR2CHTR2B | |
| SCHEMBL19067197 | 0.61 | — | — | |
| SCHEMBL18007616 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1550655-A1 | Bicyclic intermediates | Takeda Pharmaceutical Company Limited (JP) | 2005-07-06 | — | — | EP | disclosed |
| EP-0885210-B1 | Tricylic compounds having binding affinity for melatonin receptors, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2002-06-12 | — | — | EP | disclosed |
| EP-1199304-A1 | Bicyclic compounds and pharmaceutical composition containing tricyclic compound for treating or preventing sleep disorders | Takeda Chemical Industries, Ltd. (JP) | 2002-04-24 | — | — | EP | disclosed |