Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13946318 | 0.92 | C1S (0.53) | C1SMASP2 | |
| SCHEMBL4207316 | 0.91 | C1S (0.60) | C1S | |
| SCHEMBL5841073 | 0.90 | C1S (0.59) | C1SMASP2 | |
| SCHEMBL4200893 | 0.90 | C1S (0.70) | C1S | |
| SCHEMBL4202074 | 0.89 | C1S (0.50) | C1SMASP2 | |
| SCHEMBL5839556 | 0.89 | C1S (0.57) | C1S | |
| SCHEMBL4204150 | 0.87 | C1S (0.55) | C1SMASP2 | |
| SCHEMBL5841285 | 0.86 | C1S (0.58) | C1S | |
| SCHEMBL5840012 | 0.86 | C1S (0.54) | C1S | |
| SCHEMBL5839645 | 0.86 | C1S (0.55) | C1SMASP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1549632-A4 | NOVEL THIOPHENE AMIDINES, COMPOSITIONS THEREOF, AND METHODS OF TREATING COMPLEMENT-MEDIATED DISEASES AND CONDITIONS | DIMENSIONAL PHARM INC (US) | 2005-11-09 | — | — | EP | disclosed |
| EP-1549632-A1 | NOVEL THIOPHENE AMIDINES, COMPOSITIONS THEREOF, AND METHODS OF TREATING COMPLEMENT-MEDIATED DISEASES AND CONDITIONS | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 2005-07-06 | — | — | EP | disclosed |
| WO-2003099805-A1 | NOVEL THIOPHENE AMIDINES, COMPOSITIONS THEREOF, AND METHODS OF TREATING COMPLEMENT-MEDIATED DISEASES AND CONDITIONS | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 2003-12-04 | — | — | WO | disclosed |