Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6209743 | 1.00 | SMN1; SMN2 (0.43) | SMN1; SMN2LMNAPOLBALDH1A1KMT2A | |
| SCHEMBL15260667 | 0.86 | TSHR (0.36) | SMN1; SMN2LMNAPOLBALDH1A1KMT2A | |
| SCHEMBL31520536 | 0.86 | TSHR (0.36) | SMN1; SMN2LMNAPOLBALDH1A1KMT2A | |
| SCHEMBL27861942 | 0.86 | SMN1; SMN2 (0.41) | SMN1; SMN2LMNAPOLBALDH1A1KMT2A | |
| SCHEMBL696737 | 0.80 | — | — | |
| SCHEMBL31078949 | 0.78 | SMN1; SMN2 (0.44) | SMN1; SMN2LMNAPOLBALDH1A1KMT2A | |
| SCHEMBL2683916 | 0.76 | USP2 (0.39) | ALDH1A1KMT2AMEN1TSHRMAPK1 | |
| SCHEMBL29937233 | 0.75 | SMN1; SMN2 (0.42) | SMN1; SMN2LMNAPOLBALDH1A1KMT2A | |
| Oxalic Acid SCHEMBL27086649 | 0.75 | SMN1; SMN2 (0.40) | SMN1; SMN2LMNAPOLBALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL10884122 | 0.74 | USP2 (0.38) | ALDH1A1KMT2AMEN1TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1189612-A4 | VLA-4 INHIBITOR COMPOUNDS | DAIICHI SEIYAKU CO (JP) | 2005-02-16 | — | — | EP | disclosed |
| EP-1189612-A1 | VLA-4 INHIBITOR COMPOUNDS | Daiichi Pharmaceutical Co., Ltd. (JP) | 2002-03-27 | — | — | EP | disclosed |
| WO-2001000206-A1 | VLA-4 INHIBITOR COMPOUNDS | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2001-01-04 | — | — | WO | disclosed |