Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WEE1 | P30291 | 20/20 | 0.64 |
| ▸ | CHEK1 | O14757 | 18/20 | 0.64 |
| ▸ | CDK1 | P06493 | 5/20 | 0.63 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5828854 | 0.99 | WEE1 (0.63) | WEE1CHEK1CDK1CCNB1 | |
| SCHEMBL5829002 | 0.86 | WEE1 (0.66) | WEE1CHEK1CDK1CCNB1 | |
| SCHEMBL5828649 | 0.85 | WEE1 (0.62) | WEE1CHEK1CDK1CCNB1 | |
| SCHEMBL5829407 | 0.85 | WEE1 (0.71) | WEE1CHEK1CDK1CCNB1 | |
| SCHEMBL6230406 | 0.84 | WEE1 (0.70) | WEE1CHEK1CDK1CCNB1 | |
| SCHEMBL5828848 | 0.81 | WEE1 (0.71) | WEE1CHEK1CDK1CCNB1 | |
| SCHEMBL5828251 | 0.81 | WEE1 (0.74) | WEE1CHEK1CDK1CCNB1 | |
| SCHEMBL5828897 | 0.81 | WEE1 (0.75) | WEE1CHEK1CDK1CCNB1 | |
| SCHEMBL5829850 | 0.79 | WEE1 (0.70) | WEE1CHEK1CDK1CCNB1 | |
| SCHEMBL5828662 | 0.78 | WEE1 (0.64) | WEE1CHEK1CDK1CCNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1501831-A1 | INHIBITORS OF CHECKPOINT KINASES (WEE1 AND CHK1) | WARNER-LAMBERT COMPANY LLC (US) | 2005-02-02 | — | — | EP | claimed |
| WO-2003091255-A1 | INHIBITORS OF CHECKPOINT KINASES (WEE1 AND CHK1) | WARNER-LAMBERT COMPANY LLC (US) | 2003-11-06 | — | — | WO | claimed |