Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 15/20 | 0.65 |
| ▸ | DRD2 | P14416 | 8/20 | 0.63 |
| ▸ | DRD3 | P35462 | 5/20 | 0.48 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.48 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6210502 | 0.80 | DRD4 (0.68) | DRD4DRD2DRD3 | |
| SCHEMBL4003760 | 0.79 | DRD4 (1.00) | DRD4 | |
| SCHEMBL4004571 | 0.79 | DRD4 (0.70) | DRD4DRD2DRD3 | |
| SCHEMBL4005966 | 0.78 | DRD4 (1.00) | DRD4DRD2DRD3ADRA1DADRA1A | |
| SCHEMBL4006660 | 0.77 | DRD4 (0.84) | DRD4DRD2DRD3ADRA1DADRA1A | |
| SCHEMBL6215309 | 0.77 | DRD4 (0.66) | DRD4DRD2DRD3ADRA1DADRA1A | |
| SCHEMBL4004857 | 0.74 | DRD4 (1.00) | DRD4DRD2DRD3ADRA1A | |
| SCHEMBL4003763 | 0.73 | DRD4 (0.77) | DRD4DRD2DRD3 | |
| SCHEMBL6216990 | 0.71 | DRD4 (0.65) | DRD4DRD2DRD3ADRA1DADRA1A | |
| SCHEMBL4005568 | 0.71 | DRD4 (0.71) | DRD4DRD2DRD3ADRA1DADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1509213-A2 | ACETAMIDES AND BENZAMIDES THAT ARE USEFUL IN TREATING SEXUAL DYSFUNCTION | Abbott Laboratories (US) | 2005-03-02 | — | — | EP | disclosed |
| WO-2003099266-A2 | ACETAMIDES AND BENZAMIDES THAT ARE USEFUL IN TREATING SEXUAL DYSFUNCTION | ABBOTT LABORATORIES (US) | 2003-12-04 | — | — | WO | disclosed |