Sugi Predict

Sugi Predict / Compounds / SCHEMBL6213629

SCHEMBL6213629

SCHEMBL6213629

CSc1sc(C(=N)NC(=O)OC(C)(C)C)cc1S(=O)(=O)c1ccc(C)c(-c2ccccc2N2CCOCC2)c1

nearest known ligand 0.43

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ C1S P09871 20/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5841968 0.85 C1S (0.51) C1S
SCHEMBL5982710 0.79 C1S (0.43) C1S
SCHEMBL5841730 0.76 C1S (0.54) C1S
SCHEMBL5842036 0.76 C1S (0.46) C1S
SCHEMBL5842281 0.76 C1S (0.45) C1S
SCHEMBL5840331 0.75 C1S (0.54) C1S
SCHEMBL5840684 0.74 C1S (0.57) C1S
SCHEMBL4206323 0.74 C1S (0.65) C1S
SCHEMBL6210319 0.74 C1S (0.46) C1S
SCHEMBL5841046 0.73 C1S (0.54) C1S

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1549632-A4 NOVEL THIOPHENE AMIDINES, COMPOSITIONS THEREOF, AND METHODS OF TREATING COMPLEMENT-MEDIATED DISEASES AND CONDITIONS DIMENSIONAL PHARM INC (US) 2005-11-09 — — EP disclosed
EP-1549632-A1 NOVEL THIOPHENE AMIDINES, COMPOSITIONS THEREOF, AND METHODS OF TREATING COMPLEMENT-MEDIATED DISEASES AND CONDITIONS 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) 2005-07-06 — — EP disclosed
WO-2003099805-A1 NOVEL THIOPHENE AMIDINES, COMPOSITIONS THEREOF, AND METHODS OF TREATING COMPLEMENT-MEDIATED DISEASES AND CONDITIONS 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) 2003-12-04 — — WO disclosed