⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27879896 | 0.78 | — | — | |
| SCHEMBL8508616 | 0.75 | — | — | |
| SCHEMBL4392326 | 0.73 | — | — | |
| SCHEMBL8464618 | 0.73 | — | — | |
| SCHEMBL220417 | 0.72 | — | — | |
| SCHEMBL10837789 | 0.72 | CYP2C19 (0.35) | — | |
| SCHEMBL16497410 | 0.72 | — | — | |
| SCHEMBL16496905 | 0.69 | — | — | |
| SCHEMBL10838093 | 0.69 | — | — | |
| SCHEMBL11276757 | 0.69 | CYP2C19 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2421873-B1 | ALPHA-SILYL ALCOHOLS POSSESSING OLFACTORY PROPERTIES REMINISCENT OF PATCHOULI OIL | GIVAUDAN SA (CH) | 2014-07-02 | — | — | EP | disclosed |
| US-8182781-B2 | Alpha-silyl alcohols possessing olfactory properties reminiscent of patchouli oil | GIVAUDAN S.A. (CH) | 2012-05-22 | — | — | US | disclosed |
| EP-2421873-A1 | ALPHA-SILYL ALCOHOLS POSSESSING OLFACTORY PROPERTIES REMINISCENT OF PATCHOULI OIL | Givaudan SA (CH) | 2012-02-29 | — | — | EP | disclosed |
| US-20120040879-A1 | Alpha-Silyl Alcohols Possessing Olfactory Properties Reminiscent Of Patchouli Oil | GIVAUDAN SA (CH) | 2012-02-16 | — | — | US | disclosed |
| WO-2010121979-A1 | ALPHA-SILYL ALCOHOLS POSSESSING OLFACTORY PROPERTIES REMINISCENT OF PATCHOULI OIL | GIVAUDAN SA (CH) | 2010-10-28 | — | — | WO | disclosed |