Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 20/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6214496 | 1.00 | NPY5R (0.75) | NPY5R | |
| SCHEMBL6214500 | 1.00 | NPY5R (0.75) | NPY5R | |
| SCHEMBL5772708 | 0.88 | NPY5R (0.80) | NPY5R | |
| SCHEMBL6214145 | 0.86 | NPY5R (0.78) | NPY5R | |
| SCHEMBL6214153 | 0.86 | NPY5R (0.78) | NPY5R | |
| SCHEMBL5772748 | 0.86 | NPY5R (1.00) | NPY5R | |
| SCHEMBL5773648 | 0.85 | NPY5R (0.85) | NPY5R | |
| Hydrochloric Acid SCHEMBL7184079 | 0.84 | NPY5R (0.96) | NPY5R | |
| Hydrochloric Acid SCHEMBL5776449 | 0.84 | NPY5R (0.84) | NPY5R | |
| SCHEMBL5775795 | 0.84 | NPY5R (1.00) | NPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1003744-B1 | 4-AMINOPYRROLE(3,2-d) PYRIMIDINES AS NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | PFIZER PROD INC (US) | 2005-06-01 | — | — | EP | claimed |
| US-6187778-B1 | EATING AND CARDIOVASCULAR DISORDERS | PFIZER INC. | 2001-02-13 | — | — | US | claimed |
| EP-1003744-B1 | 4-AMINOPYRROLE(3,2-d) PYRIMIDINES AS NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | PFIZER PROD INC (US) | 2005-06-01 | — | — | EP | disclosed |
| US-6187778-B1 | EATING AND CARDIOVASCULAR DISORDERS | PFIZER INC. | 2001-02-13 | — | — | US | disclosed |