SCHEMBL62160

SCHEMBL62160

COC(OC)(C(=O)c1ccccc1)C(=O)c1ccccc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES1 P23141 6/20 0.62
SRC P12931 1/20 0.57
TSHR P16473 4/20 0.52
CES2 O00748 4/20 0.45
LMNA P02545 2/20 0.44
F2 P00734 1/20 0.44
ALDH1A1 P00352 2/20 0.44
DAO P14920 1/20 0.44
NAPRT Q6XQN6 1/20 0.44
HSD17B10 Q99714 3/20 0.44
TDP1 Q9NUW8 2/20 0.44
KCNN4 O15554 1/20 0.42
MAPT P10636 2/20 0.42
MAPK1 P28482 2/20 0.42
KDM4E B2RXH2 1/20 0.42
ALOX15 P16050 1/20 0.42
POLB P06746 2/20 0.41
CYP3A4 P08684 1/20 0.41
PARP1 P09874 1/20 0.41
CYP2C19 P33261 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27992104 0.91 CES1 (0.58) CES1SRCTSHRCES2LMNA
SCHEMBL28924748 0.91 CES1 (0.58) CES1SRCTSHRCES2LMNA
SCHEMBL11632725 0.88 CES1 (0.55) CES1SRCTSHRCES2LMNA
SCHEMBL11491527 0.88 SRC (0.65) CES1SRCTSHRCES2LMNA
SCHEMBL11628388 0.86 CES1 (0.53) CES1SRCTSHRCES2LMNA
SCHEMBL28140692 0.86 CES1 (0.53) CES1SRCTSHRCES2LMNA
SCHEMBL11632198 0.85 CES1 (0.51) CES1SRCTSHRCES2LMNA
SCHEMBL5146885 0.83 CES1 (0.46) CES1SRCTSHRALDH1A1HSD17B10
SCHEMBL2150284 0.82 CES1 (0.62) CES1SRCTSHRCES2LMNA
SCHEMBL28491178 0.82 CES1 (0.62) CES1SRCTSHRCES2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 416 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114699328-A Photoprotective compositions 欧莱雅 2022-07-05 CN claimed
CN-107075120-B Silicone composition crosslinking catalyst 埃肯有机硅法国有限公司 2021-02-26 CN claimed
EP-3501641-A1 MOISTURE-CURABLE COMPOSITIONS Covestro Deutschland AG (DE) 2019-06-26 EP claimed
CN-104981523-B The organopolysiloxane composition and organopolysiloxane polycondensation catalysts of elastomer-forming can be vulcanized at ambient temperature 埃肯有机硅法国简易股份公司 2018-10-09 CN claimed
CN-105008473-B Articles having antifouling properties for water applications and in particular marine applications 蓝星有机硅法国两合公司 2017-04-19 CN claimed
EP-2935492-A1 ARTICLE WITH ANTIFOULING PROPERTIES, INTENDED FOR AQUATIC USES AND, IN PARTICULAR, FOR MARINE USES Bluestar Silicones France SAS (FR) 2015-10-28 EP claimed
CN-101316577-B Personal care compositions containing silicone resins with enhanced properties and methods of making and using the same MOMENTIVE PERFORMANCE MAT INC 2015-07-15 CN claimed
CN-102223953-B Novel catalysts for the reaction between an isocyanate and an alcohol BLUESTAR SILICONES FRANCE 2015-05-20 CN claimed
WO-2014096572-A1 ARTICLE WITH ANTIFOULING PROPERTIES, INTENDED FOR AQUATIC USES AND, IN PARTICULAR, FOR MARINE USES BLUESTAR SILICONES FRANCE SAS (FR) 2014-06-26 WO claimed
CN-102223953-A Novel catalysts for the reaction between an isocyanate and an alcohol BLUESTAR SILICONES FRANCE 2011-10-19 CN claimed
CN-101986778-A Organopolysiloxane composition room temperature vulcanizable to elastomer and new organopolysiloxane polycondensation catalysts BLUESTAR SILICONES FRANCE 2011-03-16 CN claimed
WO-2009129855-A1 PHOTOPROTECTIVE COMPOSITIONS CONTAINING PEPTIDES UNITED TECHNOLOGIES UT AG (CH) 2009-10-29 WO claimed
CN-101095648-A Dibenzoylmethane sunscreens photostabilized with arylalkyl amide or ester compounds OREAL (FR) 2008-01-02 CN claimed
WO-2004022021-A1 PHOTOSTABILIZATION OF A SUNSCREEN COMPOSITION WITH AN ALPHA-CYANO-ΒΕΤΑ, ΒΕΤΑ-DIPHENYLACRYLATE CPH INNOVATIONS CORPORATION (US) 2004-03-18 WO claimed
CN-1352544-A Material containing organic UV-A sunscreen agent and method for shifting maximum absorption wavelength OREAL (FR) 2002-06-05 CN claimed
CN-1327379-A Method for improving UV radiation stability of photosensitive sunscreen filters OREAL (FR) 2001-12-19 CN claimed
EP-3709956-B1 COSMETIC OR DERMATOLOGICAL COMPOSITIONS DSM IP ASSETS BV (NL) 2024-10-23 EP disclosed
EP-4114355-B1 TOPICAL COMPOSITION COMPRISING CANNABIDIOL CURALEAF INTERNATIONAL LTD (GB) 2024-07-10 EP disclosed
EP-1025836-A1 Cosmetic light screening composition F. HOFFMANN-LA ROCHE AG (CH) 2000-08-09 EP disclosed
EP-0998906-A2 Shampoo composition F. HOFFMANN-LA ROCHE AG (CH) 2000-05-10 EP disclosed