⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL183702 | 0.87 | — | — | |
| SCHEMBL8936338 | 0.82 | — | — | |
| SCHEMBL302044 | 0.76 | — | — | |
| SCHEMBL183352 | 0.73 | — | — | |
| SCHEMBL183001 | 0.69 | — | — | |
| SCHEMBL1894280 | 0.66 | — | — | |
| SCHEMBL7109 | 0.66 | — | — | |
| SCHEMBL2088202 | 0.66 | HMGCR (0.50) | — | |
| SCHEMBL2085382 | 0.66 | HMGCR (0.50) | — | |
| SCHEMBL3625740 | 0.66 | HMGCR (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2009 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050171078-A1 | Novel azacyclic ethynyl derivatives | NEUROSEARCH (DK) | 2005-08-04 | — | — | US | claimed |
| EP-1506205-A2 | NOVEL AZACYCLIC ETHYNYL DERIVATIVES | NEUROSEARCH A/S (DK) | 2005-02-16 | — | — | EP | claimed |
| WO-2003094830-A2 | NOVEL AZACYCLIC ETHYNYL DERIVATIVES | NEUROSEARCH A/S (DK) | 2003-11-20 | — | — | WO | claimed |
| EP-0905118-B1 | Unsaturated 6-tert-butyl-1,1-dimethylindane derivates substituted in the 4-position and their use in human and veterinary medicine as well as in cosmetics | GALDERMA RES & DEV (FR) | 2001-08-16 | — | — | EP | claimed |
| EP-0905118-A1 | Unsaturated 6-tert-butyl-1,1-dimethylindane derivates substituted in the 4-position and their use in human and veterinary medicine as well as in cosmetics | Galderma Research & Development, S.N.C. (FR) | 1999-03-31 | — | — | EP | claimed |
| US-12043688-B2 | Nickel catalysts with two alkali ions for homopolymerization and copolymerization | UNIVERSITY OF HOUSTON SYSTEM (US) | 2024-07-23 | — | — | US | disclosed |
| US-12042479-B2 | Use of topical formulations of cannabinoids in the treatment of epidermolysis bullosa and related connective tissue disorders | INMED PHARMACEUTICALS INC. | 2024-07-23 | — | — | US | disclosed |
| US-12043689-B2 | Nickel catalysts with single metal cations for homopolymerization and copolymerization | UNIVERSITY OF HOUSTON SYSTEM (US) | 2024-07-23 | — | — | US | disclosed |
| US-20240239751-A1 | PROCESSES FOR PREPARING AG-10, ITS INTERMEDIATES, AND SALTS THEREOF | BRIDGEBIO GENE THERAPY RESEARCH, INC. | 2024-07-18 | — | — | US | disclosed |
| US-20240239807-A1 | SARS-COV2 MAIN PROTEASE INHIBITORS | GILEAD SCIENCES, INC. | 2024-07-18 | — | — | US | disclosed |
| US-20240238427-A1 | METHODS OF TREATING AN EYE DISORDER | KODIAK SCIENCES INC. | 2024-07-18 | — | — | US | disclosed |
| CN-118344348-A | Heterocyclic substituted quinazoline and preparation method and application thereof | 苏州泽璟生物制药股份有限公司 | 2024-07-16 | — | — | CN | disclosed |
| US-4971994-A | INSECTICIDES, MITICIDES | CIBA-GEIGY CORPORATION (US) | 1990-11-20 | — | — | US | disclosed |
| US-4908383-A | Pesticides | CIBA-GEIGY CORPORATION (US) | 1990-03-13 | — | — | US | disclosed |
| US-4855449-A | Prostacyclin (PGI2) analogues | SHIONOGI & CO., LTD. (JP) | 1989-08-08 | — | — | US | disclosed |
| US-4820836-A | ANTICOAGULANTS, ANTIULCER AGENTS | SHIONOGI & CO., LTD. (JP) | 1989-04-11 | — | — | US | disclosed |
| EP-0276823-A2 | 14,15-Substituted lanosterols and their use as hypocholesterolemic agents | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1988-08-03 | — | — | EP | disclosed |
| EP-0240890-A2 | Prostacyclin (PGI2) analogues | SHIONOGI & CO., LTD. (JP) | 1987-10-14 | — | — | EP | disclosed |
| EP-0177353-A2 | Thiazolidinedione derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1986-04-09 | — | — | EP | disclosed |
| US-4119627-A | Process for the manufacture of 6β,7-methylene-3-oxo-4-ene steroids | CIBA-GEIGY CORPORATION (US) | 1978-10-10 | — | — | US | disclosed |