SCHEMBL6217533

SCHEMBL6217533

Fc1cc(F)cc(C#CCOc2nsnc2C2CN3CCC2C3)c1

nearest known ligand 0.74

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 14/20 0.74
CHRM1 P11229 12/20 0.74

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6197487 0.94 CHRM2 (0.75) CHRM2CHRM1
SCHEMBL6217793 0.93 CHRM2 (0.68) CHRM2CHRM1
SCHEMBL6215678 0.93 CHRM2 (0.68) CHRM2CHRM1
SCHEMBL6198924 0.90 CHRM2 (0.81) CHRM2CHRM1
SCHEMBL6198071 0.88 CHRM2 (0.68) CHRM2CHRM1
SCHEMBL6199349 0.88 CHRM2 (0.68) CHRM2CHRM1
SCHEMBL6200223 0.88 CHRM2 (0.69) CHRM2CHRM1
SCHEMBL6218415 0.88 CHRM2 (0.69) CHRM2CHRM1
SCHEMBL6213940 0.88 CHRM2 (0.69) CHRM2CHRM1
SCHEMBL6197795 0.85 CHRM2 (1.00) CHRM2CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0977755-B1 HETEROCYCLIC COMPOUNDS AND THEIR PREPARATION AND USE NOVO NORDISK AS (DK) 2005-07-13 EP claimed