Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | JAK3 | P52333 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8396819 | 0.81 | TDP1 (0.44) | KMT2ACHRNA7MAPTHTTTDP1 | |
| SCHEMBL3033731 | 0.78 | MCL1 (0.44) | KMT2AMAPTHTTTDP1 | |
| SCHEMBL8396484 | 0.78 | TDP1 (0.41) | KMT2ACHRNA7MAPTHTTTDP1 | |
| SCHEMBL13495897 | 0.77 | KMT2A (0.38) | KMT2AJAK3SIGMAR1 | |
| SCHEMBL8396555 | 0.77 | MCL1 (0.43) | KMT2AMAPTHTTTDP1 | |
| SCHEMBL8394538 | 0.77 | MCL1 (0.43) | KMT2AMAPTHTTTDP1 | |
| SCHEMBL5168305 | 0.77 | MCL1 (0.43) | KMT2AMAPTHTTTDP1 | |
| SCHEMBL407286 | 0.71 | KMT2A (0.53) | KMT2A | |
| Hydrochloric Acid SCHEMBL440964 | 0.70 | KMT2A (0.56) | KMT2A | |
| SCHEMBL6557530 | 0.70 | HTT (0.38) | KMT2ACHRNB2CHRNB4CHRNA3CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1188744-B1 | Process for producing optically active 1H-3-aminopyrrolidine and derivatives thereof | MITSUBISHI CHEM CORP (JP) | 2005-11-02 | — | — | EP | claimed |