Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 11/20 | 0.42 |
| ▸ | PPARD | Q03181 | 9/20 | 0.42 |
| ▸ | PPARG | P37231 | 7/20 | 0.42 |
| ▸ | TNF | P01375 | 1/20 | 0.38 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13647505 | 0.86 | PPARA (0.49) | PPARAPPARDPPARG | |
| SCHEMBL6245155 | 0.81 | PPARA (0.42) | PPARAPPARDPPARGTNFNOD1 | |
| SCHEMBL5942862 | 0.81 | PPARD (0.39) | PPARAPPARDPPARG | |
| SCHEMBL3931085 | 0.81 | PPARD (0.47) | PPARAPPARDPPARG | |
| SCHEMBL3920688 | 0.80 | KDM4E (0.43) | PPARAPPARDPPARGTNFNOD1 | |
| SCHEMBL3917600 | 0.80 | TNF (0.40) | TNFNOD1MAPTKIF11NR1H4 | |
| SCHEMBL3927322 | 0.79 | PPARD (0.53) | PPARAPPARDPPARG | |
| SCHEMBL3918923 | 0.79 | PPARD (0.71) | PPARAPPARDPPARG | |
| SCHEMBL6249086 | 0.79 | PPARD (0.45) | PPARAPPARDPPARG | |
| SCHEMBL13647507 | 0.79 | PPARD (0.53) | PPARAPPARDPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1585726-A1 | FUSED HETEROCYCLIC DERIVATIVES AS PPAR MODULATORS | ELI LILLY AND COMPANY (US) | 2005-10-19 | — | — | EP | disclosed |
| WO-2004063155-A1 | FUSED HETEROCYCLIC DERIVATIVES AS PPAR MODULATORS | ELI LILLY AND COMPANY (US) | 2004-07-29 | — | — | WO | disclosed |