SCHEMBL6218873

SCHEMBL6218873

CCCCCCCN(CC=CC(=O)O)C1CCN(C[C@H](O)c2ccnc3ccc(OC)cc23)CC1

nearest known ligand 0.56

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SLC2A1 P11166 8/20 0.56
KCNH2 Q12809 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL5927283 0.99 SLC2A1 (0.55) SLC2A1KCNH2
SCHEMBL5927428 0.92 SLC2A1 (0.54) SLC2A1KCNH2
SCHEMBL6217501 0.89 SLC2A1 (0.59) SLC2A1KCNH2
Oxalic Acid SCHEMBL5927017 0.87 SLC2A1 (0.58) SLC2A1KCNH2
SCHEMBL6215120 0.87 SLC2A1 (0.58) SLC2A1KCNH2
SCHEMBL5927435 0.86 SLC2A1 (0.57) SLC2A1KCNH2
Oxalic Acid SCHEMBL5927510 0.86 SLC2A1 (0.56) SLC2A1KCNH2
SCHEMBL6218018 0.86 SLC2A1 (0.57) SLC2A1KCNH2
SCHEMBL6217900 0.85 SLC2A1 (0.57) SLC2A1KCNH2
Hydrochloric Acid SCHEMBL5927412 0.85 SLC2A1 (0.56) SLC2A1KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1214314-B1 AMINOPIPERIDINE DERIVATIVES AS ANTIBACTERIALS SMITHKLINE BEECHAM PLC (GB) 2005-09-07 EP claimed