SCHEMBL6219087

SCHEMBL6219087

N#Cc1cccc(C#CCOc2nsnc2C2CN3CCC2C3)c1

nearest known ligand 0.79

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 13/20 0.79
CHRM1 P11229 11/20 0.79

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6200051 0.94 CHRM2 (0.79) CHRM2CHRM1
SCHEMBL21802372 0.90 CHRM2 (0.86) CHRM2CHRM1
SCHEMBL6218653 0.89 CHRM2 (0.79) CHRM2CHRM1
SCHEMBL6220594 0.89 CHRM2 (0.79) CHRM2CHRM1
SCHEMBL6219786 0.89 CHRM2 (0.79) CHRM2CHRM1
SCHEMBL6197795 0.88 CHRM2 (1.00) CHRM2CHRM1
SCHEMBL6198925 0.87 CHRM2 (0.76) CHRM2CHRM1
SCHEMBL6213064 0.85 CHRM2 (0.72) CHRM2CHRM1
SCHEMBL6198189 0.84 CHRM2 (0.78) CHRM2CHRM1
SCHEMBL6198888 0.84 CHRM2 (0.78) CHRM2CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0977755-B1 HETEROCYCLIC COMPOUNDS AND THEIR PREPARATION AND USE NOVO NORDISK AS (DK) 2005-07-13 EP claimed