Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 11/20 | 0.47 |
| ▸ | PPARG | P37231 | 10/20 | 0.47 |
| ▸ | PPARD | Q03181 | 12/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3927910 | 0.92 | PPARD (0.51) | PPARAPPARGPPARDMTNR1AMTNR1B | |
| SCHEMBL6217695 | 0.87 | PPARD (0.63) | PPARAPPARGPPARD | |
| SCHEMBL3922998 | 0.84 | PPARG (0.45) | PPARAPPARGPPARD | |
| SCHEMBL13647652 | 0.84 | PPARG (0.44) | PPARAPPARGPPARDMTNR1AMTNR1B | |
| SCHEMBL6218264 | 0.82 | PPARD (0.53) | PPARAPPARGPPARD | |
| SCHEMBL3922268 | 0.81 | PPARD (0.53) | PPARAPPARGPPARD | |
| SCHEMBL3918024 | 0.78 | PPARD (0.70) | PPARAPPARGPPARD | |
| SCHEMBL3924068 | 0.78 | PPARD (0.52) | PPARAPPARGPPARD | |
| SCHEMBL6218511 | 0.78 | PPARA (0.51) | PPARAPPARGPPARD | |
| SCHEMBL5852547 | 0.77 | PPARA (0.51) | PPARAPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1585726-A1 | FUSED HETEROCYCLIC DERIVATIVES AS PPAR MODULATORS | ELI LILLY AND COMPANY (US) | 2005-10-19 | — | — | EP | disclosed |
| WO-2004063155-A1 | FUSED HETEROCYCLIC DERIVATIVES AS PPAR MODULATORS | ELI LILLY AND COMPANY (US) | 2004-07-29 | — | — | WO | disclosed |