Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 9/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.37 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6222230 | 0.81 | MC4R (0.60) | MC4RKCNH2ALDH1A1GAAMAPT | |
| SCHEMBL3090264 | 0.81 | MC4R (0.52) | MC4RKCNH2ALDH1A1GAAMAPT | |
| SCHEMBL3072124 | 0.80 | MC4R (0.60) | MC4RKCNH2ALDH1A1GAAMAPT | |
| SCHEMBL6222542 | 0.78 | MC4R (0.64) | MC4RKCNH2 | |
| SCHEMBL3085659 | 0.78 | MC4R (0.55) | MC4RKCNH2ALDH1A1GAAMAPT | |
| SCHEMBL3089929 | 0.74 | MC4R (0.67) | MC4RKCNH2 | |
| SCHEMBL3095645 | 0.74 | MC4R (0.68) | MC4R | |
| SCHEMBL3084386 | 0.74 | MC4R (0.61) | MC4RKCNH2 | |
| SCHEMBL3082228 | 0.72 | MC4R (0.75) | MC4R | |
| SCHEMBL3095821 | 0.71 | MC4R (0.70) | MC4RALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1590338-A2 | MODULATORS OF MELANOCORTIN RECEPTOR | Gene Logic Inc. (US) | 2005-11-02 | — | — | EP | disclosed |
| WO-2004050610-A2 | MODULATORS OF MELANOCORTIN RECEPTOR | GENE LOGIC INC. (US) | 2004-06-17 | — | — | WO | disclosed |