Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 6/20 | 0.32 |
| ▸ | POLB | P06746 | 5/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3986099 | 1.00 | TSHR (0.34) | TSHRTP53POLBRXFP1MAPT | |
| SCHEMBL3987978 | 0.93 | TSHR (0.34) | TSHRPOLBPDE10ARECQL | |
| SCHEMBL6218685 | 0.91 | TSHR (0.34) | TSHRPOLBPDE10A | |
| SCHEMBL3988459 | 0.91 | TSHR (0.34) | TSHRPOLBPDE10A | |
| SCHEMBL3991236 | 0.91 | TSHR (0.34) | TSHRPOLBPDE10A | |
| SCHEMBL4470123 | 0.91 | TSHR (0.33) | TSHR | |
| SCHEMBL4473555 | 0.90 | TSHR (0.36) | TSHRTP53POLBRXFP1MAPT | |
| SCHEMBL3987690 | 0.89 | TSHR (0.39) | TSHRTP53POLBRXFP1MAPT | |
| SCHEMBL3987234 | 0.89 | TSHR (0.35) | TSHRTP53POLBRXFP1MAPT | |
| SCHEMBL3993117 | 0.89 | TSHR (0.38) | TSHRTP53POLBRXFP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1597246-A2 | INHIBITORS OF HEPATITIS C VIRUS RNA-DEPENDENT RNA POLYMERASE, AND COMPOSITIONS AND TREATMENTS USING THE SAME | PFIZER INC. (US) | 2005-11-23 | — | — | EP | disclosed |
| WO-2004074270-A2 | INHIBITORS OF HEPATITIS C VIRUS RNA-DEPENDENT RNA POLYMERASE, AND COMPOSITIONS AND TREATMENTS USING THE SAME | PFIZER INC. (US) | 2004-09-02 | — | — | WO | disclosed |