Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD52 | P43351 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | AR | P10275 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CDK1 | P06493 | 2/20 | 0.38 |
| ▸ | CDK2 | P24941 | 2/20 | 0.38 |
| ▸ | LGMN | Q99538 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1537907 | 0.90 | RAD52 (0.51) | RAD52GAATHRBMAPTKDM4E | |
| Hydrochloric Acid SCHEMBL5383213 | 0.89 | RAD52 (0.50) | RAD52GAATHRBMAPTKDM4E | |
| SCHEMBL6706979 | 0.86 | RAD52 (0.53) | RAD52GAATHRBMAPTKDM4E | |
| SCHEMBL6221179 | 0.83 | GAA (0.50) | RAD52GAATHRBMAPTKDM4E | |
| SCHEMBL6709032 | 0.81 | GAA (0.54) | RAD52GAATHRBMAPTKDM4E | |
| SCHEMBL6710488 | 0.81 | GAA (0.48) | RAD52GAATHRBMAPTKDM4E | |
| SCHEMBL6254071 | 0.81 | GAA (0.55) | RAD52GAATHRBMAPTKDM4E | |
| SCHEMBL5202869 | 0.80 | GAA (0.51) | RAD52GAATHRBMAPTKDM4E | |
| SCHEMBL6220205 | 0.80 | GAA (0.58) | RAD52GAATHRBMAPTKDM4E | |
| SCHEMBL6746065 | 0.80 | RAD52 (0.45) | RAD52GAATHRBMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1512684-A1 | use of derivative of para-phenylenediamine substituted by a homopiperidine ring, for the dyeing of keratinous fibres | L'OREAL (FR) | 2005-03-09 | — | — | EP | claimed |
| EP-1512684-A1 | use of derivative of para-phenylenediamine substituted by a homopiperidine ring, for the dyeing of keratinous fibres | L'OREAL (FR) | 2005-03-09 | — | — | EP | disclosed |
| EP-1512684-A1 | use of derivative of para-phenylenediamine substituted by a homopiperidine ring, for the dyeing of keratinous fibres | L'OREAL (FR) | 2005-03-09 | — | — | EP | disclosed |