Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | CFTR | P13569 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | NAMPT | P43490 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18945578 | 1.00 | KDM4E (0.61) | KDM4ESMN1; SMN2CFTRSLC6A2SLC6A4 | |
| SCHEMBL8012590 | 0.83 | KDM4E (0.65) | KDM4ESMN1; SMN2CFTRSLC6A2SLC6A4 | |
| SCHEMBL13081367 | 0.82 | KDM4E (0.62) | KDM4ESMN1; SMN2CFTRSLC6A2SLC6A4 | |
| SCHEMBL2373412 | 0.82 | KDM4E (0.62) | KDM4ESMN1; SMN2CFTRSLC6A2SLC6A4 | |
| SCHEMBL1487951 | 0.80 | KDM4E (0.61) | KDM4ESMN1; SMN2CFTRSLC6A2SLC6A4 | |
| SCHEMBL6583342 | 0.80 | KDM4E (0.61) | KDM4ESMN1; SMN2CFTRSLC6A2SLC6A4 | |
| SCHEMBL10061711 | 0.78 | POLB (0.60) | KDM4ECYP2C9NAMPTPOLB | |
| SCHEMBL14277947 | 0.78 | POLB (0.60) | KDM4ECYP2C9NAMPTPOLB | |
| SCHEMBL6222176 | 0.78 | KDM4E (0.58) | KDM4ESMN1; SMN2CYP2C9NAMPTPOLB | |
| SCHEMBL19322924 | 0.78 | POLB (0.60) | KDM4ECYP2C9NAMPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2927218-B1 | TETRAZOLINONE COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL CO (JP) | 2018-07-04 | — | — | EP | disclosed |
| EP-1539159-A1 | SULPHONYLPIPERIDINE DERIVATIVES CONTAINING AN ARYL OR HETEROARYL GROUP FOR USE AS MATRIX METALLOPROTEINASE INHIBITORS | Astrazeneca AB (SE) | 2005-06-15 | — | — | EP | disclosed |
| WO-2004006926-A1 | SULPHONYLPIPERIDINE DERIVATIVES CONTAINING AN ARYL OR HETEROARYL GROUP FOR USE AS MATRIX METALLOPROTEINASE INHIBITORS | ASTRAZENECA AB (SE) | 2004-01-22 | — | — | WO | disclosed |