SCHEMBL6220847

SCHEMBL6220847

Cc1ncc2n1C(=O)N(C1CCN(C(=O)[C@H](CNC(=O)O)CS(=O)(=O)c3ccc4cc(Cl)ccc4c3)CC1)C2

nearest known ligand 0.79

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
F10 P00742 20/20 0.79
F2 P00734 4/20 0.79
F9 P00740 1/20 0.48
PLAT P00750 1/20 0.48
KLKB1 P03952 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5446139 1.00 F10 (0.79) F10F2F9PLATKLKB1
SCHEMBL949850 0.91 F10 (0.83) F10F2F9PLATKLKB1
SCHEMBL947695 0.89 F10 (0.77) F10F2F9PLATKLKB1
SCHEMBL6221223 0.88 F10 (0.81) F10F2F9PLATKLKB1
SCHEMBL6217600 0.88 F10 (0.81) F10F2F9PLATKLKB1
SCHEMBL950594 0.88 F10 (1.00) F10F2F9PLATKLKB1
SCHEMBL947904 0.88 F10 (1.00) F10F2F9PLATKLKB1
SCHEMBL949001 0.88 F10 (1.00) F10F2F9PLATKLKB1
Hydrochloric Acid SCHEMBL949099 0.88 F10 (0.98) F10F2F9PLATKLKB1
SCHEMBL947693 0.87 F10 (0.79) F10F2F9PLATKLKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1564213-A1 IMIDAZOLE DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND USE Takeda Pharmaceutical Company Limited (JP) 2005-08-17 EP disclosed