Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 15/20 | 0.48 |
| ▸ | PPARA | Q07869 | 10/20 | 0.48 |
| ▸ | PPARG | P37231 | 7/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 8/20 | 0.46 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4470189 | 0.91 | PPARD (0.48) | PPARDPPARAPPARGFFAR1CHRM5 | |
| SCHEMBL4477011 | 0.86 | PPARD (0.47) | PPARDPPARAPPARGFFAR1CHRM5 | |
| SCHEMBL4477087 | 0.79 | PPARD (0.53) | PPARDPPARAPPARGFFAR1CHRM5 | |
| SCHEMBL4463450 | 0.79 | PPARD (0.44) | PPARDPPARAPPARGFFAR1 | |
| SCHEMBL6220268 | 0.78 | PPARD (0.39) | PPARDPPARAPPARGFFAR1 | |
| SCHEMBL6103483 | 0.78 | PPARD (0.61) | PPARDPPARAPPARGFFAR1 | |
| SCHEMBL5516718 | 0.77 | PPARD (0.79) | PPARDPPARAPPARGFFAR1 | |
| SCHEMBL3540426 | 0.76 | MAPT (0.43) | PPARDPPARAPPARGFFAR1 | |
| SCHEMBL6220491 | 0.76 | PPARD (0.46) | PPARDPPARAPPARGFFAR1 | |
| SCHEMBL4469584 | 0.76 | MAPT (0.44) | PPARDPPARAPPARGFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1581491-A1 | INDOLE DERIVATIVES AS PPAR MODULATORS | ELI LILLY AND COMPANY (US) | 2005-10-05 | — | — | EP | disclosed |
| WO-2004092131-A1 | INDOLE DERIVATIVES AS PPAR MODULATORS | ELI LILLY AND COMPANY (US) | 2004-10-28 | — | — | WO | disclosed |