Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 15/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3072120 | 0.91 | MC4R (0.64) | MC4RALDH1A1GAAMAPTMCHR1 | |
| SCHEMBL3082223 | 0.86 | MC4R (0.64) | MC4RALDH1A1GAAMAPTMCHR1 | |
| SCHEMBL14193875 | 0.84 | MC4R (0.58) | MC4RALDH1A1GAAMAPT | |
| SCHEMBL3077931 | 0.83 | MC4R (0.73) | MC4RALDH1A1GAAMAPTMCHR1 | |
| SCHEMBL3082228 | 0.82 | MC4R (0.75) | MC4R | |
| SCHEMBL6222230 | 0.82 | MC4R (0.60) | MC4RALDH1A1GAAMAPT | |
| SCHEMBL3085659 | 0.80 | MC4R (0.55) | MC4RALDH1A1GAAMAPT | |
| SCHEMBL3095881 | 0.79 | MC4R (0.59) | MC4RALDH1A1GAAMAPT | |
| SCHEMBL3077933 | 0.78 | MC4R (1.00) | MC4R | |
| SCHEMBL13146998 | 0.78 | MC4R (0.54) | MC4RALDH1A1GAAMAPTMCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1590338-A2 | MODULATORS OF MELANOCORTIN RECEPTOR | Gene Logic Inc. (US) | 2005-11-02 | — | — | EP | disclosed |
| WO-2004050610-A2 | MODULATORS OF MELANOCORTIN RECEPTOR | GENE LOGIC INC. (US) | 2004-06-17 | — | — | WO | disclosed |