Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 20/20 | 0.71 |
| ▸ | WNT1 | P04628 | 10/20 | 0.71 |
| ▸ | CLK2 | P49760 | 3/20 | 0.69 |
| ▸ | CLK3 | P49761 | 3/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5915911 | 0.91 | DYRK1A (0.63) | DYRK1AWNT1CLK2CLK3 | |
| SCHEMBL82928 | 0.90 | DYRK1A (0.71) | DYRK1AWNT1CLK2CLK3 | |
| SCHEMBL14792220 | 0.88 | DYRK1A (0.73) | DYRK1AWNT1CLK2CLK3 | |
| SCHEMBL14804410 | 0.87 | DYRK1A (0.76) | DYRK1AWNT1CLK2CLK3 | |
| SCHEMBL5716427 | 0.87 | DYRK1A (0.82) | DYRK1AWNT1CLK2CLK3 | |
| SCHEMBL6223964 | 0.87 | DYRK1A (0.78) | DYRK1AWNT1CLK2CLK3 | |
| SCHEMBL6225337 | 0.86 | DYRK1A (0.65) | DYRK1AWNT1CLK2CLK3 | |
| Hydrochloric Acid SCHEMBL952393 | 0.86 | DYRK1A (0.80) | DYRK1AWNT1CLK2CLK3 | |
| SCHEMBL14785604 | 0.85 | DYRK1A (0.84) | DYRK1AWNT1CLK2CLK3 | |
| SCHEMBL5916093 | 0.85 | DYRK1A (0.62) | DYRK1AWNT1CLK2CLK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1549620-A1 | INDAZOLECARBOXAMIDE DERIVATIVES, PREPARATION AND USE THEREOF AS CDK1, CDK2 AND CDK4 INHIBITORS | Sanofi-Aventis (FR) | 2005-07-06 | — | — | EP | claimed |
| WO-2004031158-A1 | INDAZOLECARBOXAMIDE DERIVATIVES, PREPARATION AND USE THEREOF AS CDK1, CDK2 AND CDK4 INHIBITORS | SANOFI-AVENTIS (FR) | 2004-04-15 | — | — | WO | claimed |