Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH2 | P25021 | 17/20 | 0.56 |
| ▸ | HTR2A | P28223 | 2/20 | 0.49 |
| ▸ | HTR2C | P28335 | 2/20 | 0.49 |
| ▸ | HTR2B | P41595 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6222774 | 0.91 | HRH2 (0.64) | HRH2HTR2AHTR2CHTR2B | |
| SCHEMBL4060062 | 0.82 | HRH2 (0.69) | HRH2HTR2AHTR2CHTR2B | |
| SCHEMBL4053924 | 0.81 | HRH2 (0.81) | HRH2HTR2AHTR2CHTR2B | |
| SCHEMBL4054609 | 0.79 | HRH2 (0.67) | HRH2HTR2AHTR2CHTR2B | |
| SCHEMBL4053895 | 0.78 | HRH2 (0.75) | HRH2HTR2AHTR2CHTR2B | |
| SCHEMBL4055187 | 0.77 | HRH2 (0.80) | HRH2HTR2AHTR2CHTR2B | |
| SCHEMBL4052175 | 0.76 | HRH2 (0.69) | HRH2HTR2AHTR2CHTR2B | |
| SCHEMBL6780025 | 0.75 | HRH2 (0.84) | HRH2HTR2AHTR2CHTR2B | |
| SCHEMBL4051054 | 0.74 | HRH2 (0.81) | HRH2HTR2AHTR2CHTR2B | |
| SCHEMBL4058973 | 0.74 | HRH2 (0.51) | HRH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1497292-A1 | AZAINDOLYLPIPERIDINE DERIVATIVES AS ANTIHISTAMINIC AND ANTIALLERGIC AGENTS | Almirall Prodesfarma, S.A. (ES) | 2005-01-19 | — | — | EP | claimed |
| WO-2003082867-A1 | AZAINDOLYLPIPERIDINE DERIVATIVES AS ANTIHISTAMINIC AND ANTIALLERGIC AGENTS | ALMIRALL PRODESFARMA S.A. (ES) | 2003-10-09 | — | — | WO | claimed |