Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.47 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | CA1 | P00915 | 3/20 | 0.44 |
| ▸ | CA2 | P00918 | 3/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA7 | P43166 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | XDH | P47989 | 1/20 | 0.41 |
| ▸ | HPGDS | O60760 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7419598 | 0.88 | MAPK1 (0.57) | MAPK1KDM4EL3MBTL1S1PR4S1PR3 | |
| SCHEMBL28230930 | 0.85 | MAPK1 (0.57) | MAPK1KDM4EL3MBTL1S1PR4S1PR3 | |
| SCHEMBL179293 | 0.84 | MAPK1 (0.61) | MAPK1KDM4EL3MBTL1S1PR4S1PR3 | |
| SCHEMBL31601530 | 0.84 | MAPK1 (0.53) | MAPK1KDM4EL3MBTL1S1PR4S1PR3 | |
| SCHEMBL28356445 | 0.84 | MAPK1 (0.53) | MAPK1KDM4EL3MBTL1S1PR4S1PR3 | |
| SCHEMBL796852 | 0.83 | MAPK1 (0.59) | MAPK1KDM4EL3MBTL1S1PR4S1PR3 | |
| SCHEMBL14636332 | 0.83 | MAPK1 (0.59) | MAPK1KDM4EL3MBTL1S1PR4S1PR3 | |
| SCHEMBL6226826 | 0.83 | MAPK1 (0.59) | MAPK1KDM4EL3MBTL1S1PR4S1PR3 | |
| SCHEMBL3645881 | 0.81 | MAPK1 (0.57) | MAPK1KDM4EL3MBTL1S1PR4S1PR3 | |
| SCHEMBL13290278 | 0.81 | MAPK1 (0.57) | MAPK1KDM4EL3MBTL1S1PR4S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113461608-B | Synthetic method of 6-formyl methyl nicotinate | 江苏弘和药物研发有限公司 | 2023-03-17 | — | — | CN | claimed |
| CN-113461608-A | Synthetic method of 6-formyl methyl nicotinate | 江苏弘和药物研发有限公司 | 2021-10-01 | — | — | CN | claimed |
| CN-117800904-A | ROR gamma inhibitors containing sulfonyl structures | 正大天晴药业集团股份有限公司 | 2024-04-02 | — | — | CN | disclosed |
| CN-113166061-B | ROR gamma inhibitors containing sulfonyl structures | 正大天晴药业集团股份有限公司 | 2023-11-21 | — | — | CN | disclosed |
| CN-113461608-B | Synthetic method of 6-formyl methyl nicotinate | 江苏弘和药物研发有限公司 | 2023-03-17 | — | — | CN | disclosed |
| CN-113461608-B | Synthetic method of 6-formyl methyl nicotinate | 江苏弘和药物研发有限公司 | 2023-03-17 | — | — | CN | disclosed |
| CN-113461608-A | Synthetic method of 6-formyl methyl nicotinate | 江苏弘和药物研发有限公司 | 2021-10-01 | — | — | CN | disclosed |
| CN-113166061-A | ROR gamma inhibitors containing sulfonyl structures | 正大天晴药业集团股份有限公司 | 2021-07-23 | — | — | CN | disclosed |
| EP-1534689-A1 | NOVEL CARBOXAMIDE COMPOUNDS HAVING AN MCH-ANTAGONISTIC EFFECT, MEDICAMENTS CONTAINING SAID COMPOUNDS, AND METHODS FOR THE PRODUCTION THEREOF | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2005-06-01 | — | — | EP | disclosed |
| US-20040242572-A1 | New carboxamide compounds having melanin concentrating hormone antagonistic activity, pharmaceutical preparations comprising these compounds and process for their manufacture | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2004-12-02 | — | — | US | disclosed |
| EP-1268449-A4 | SUBSTITUTED PIPERIDINES AS MELANOCORTIN RECEPTOR AGONISTS | MERCK & CO INC (US) | 2004-09-15 | — | — | EP | disclosed |
| WO-2004024702-A1 | NOVEL CARBOXAMIDE COMPOUNDS HAVING AN MCH-ANTAGONISTIC EFFECT, MEDICAMENTS CONTAINING SAID COMPOUNDS, AND METHODS FOR THE PRODUCTION THEREOF | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2004-03-25 | — | — | WO | disclosed |
| EP-1268449-A1 | SUBSTITUTED PIPERIDINES AS MELANOCORTIN RECEPTOR AGONISTS | Merck & Co., Inc. (US) | 2003-01-02 | — | — | EP | disclosed |
| WO-2001070708-A1 | SUBSTITUTED PIPERIDINES AS MELANOCORTIN RECEPTOR AGONISTS | MERCK & CO., INC. (US) | 2001-09-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040242572-A1 | New carboxamide compounds having melanin concentrating hormone antagonistic activity, pharmaceutical preparations comprising these compounds and process for their manufacture | MCHR2, MCHR1, NPY1R | MAPK1 3295/4885KDM4E 492/4885L3MBTL1 3619/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.