Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.66 |
| ▸ | MAPT | P10636 | 9/20 | 0.66 |
| ▸ | MEN1 | O00255 | 4/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.64 |
| ▸ | NPC1 | O15118 | 3/20 | 0.64 |
| ▸ | RAB9A | P51151 | 3/20 | 0.64 |
| ▸ | LMNA | P02545 | 7/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | HPGD | P15428 | 3/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | HTT | P42858 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6026781 | 0.86 | MEN1 (0.75) | KDM4EMAPTMEN1KMT2ANPC1 | |
| SCHEMBL6026902 | 0.82 | NPC1 (0.64) | KDM4EMAPTMEN1KMT2ANPC1 | |
| SCHEMBL6026771 | 0.82 | NPC1 (0.78) | KDM4EMAPTMEN1KMT2ANPC1 | |
| SCHEMBL6220417 | 0.81 | MEN1 (0.60) | KDM4EMAPTMEN1KMT2ANPC1 | |
| SCHEMBL29360828 | 0.81 | NPC1 (0.77) | KDM4EMAPTMEN1KMT2ANPC1 | |
| SCHEMBL1101199 | 0.81 | NPC1 (0.77) | KDM4EMAPTMEN1KMT2ANPC1 | |
| SCHEMBL6027354 | 0.81 | NPC1 (0.62) | KDM4EMAPTMEN1KMT2ANPC1 | |
| Hydrochloric Acid SCHEMBL4754679 | 0.80 | NPC1 (0.74) | KDM4EMAPTMEN1KMT2ANPC1 | |
| SCHEMBL6026657 | 0.80 | NPC1 (0.74) | KDM4EMAPTMEN1KMT2ANPC1 | |
| SCHEMBL20068101 | 0.79 | MEN1 (0.60) | KDM4EMAPTMEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1266887-B1 | Indenoindoline derivatives, their process of preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2005-08-17 | — | — | EP | disclosed |