Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 19/20 | 0.69 |
| ▸ | RAF1 | P04049 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6249917 | 0.91 | EPHX2 (0.66) | EPHX2RAF1CA12CA1CA2 | |
| SCHEMBL6228091 | 0.89 | EPHX2 (0.71) | EPHX2 | |
| SCHEMBL4345603 | 0.85 | CA12 (0.54) | CA12CA1CA2CA9 | |
| SCHEMBL6255295 | 0.84 | EPHX2 (0.62) | EPHX2 | |
| SCHEMBL6224093 | 0.83 | EPHX2 (0.69) | EPHX2RAF1 | |
| SCHEMBL4347622 | 0.83 | EPHX2 (0.60) | EPHX2 | |
| SCHEMBL6250598 | 0.82 | EPHX2 (0.76) | EPHX2RAF1CA12CA1CA2 | |
| SCHEMBL6225545 | 0.82 | EPHX2 (0.76) | EPHX2RAF1CA12CA1CA2 | |
| SCHEMBL6226060 | 0.81 | EPHX2 (0.65) | EPHX2RAF1 | |
| SCHEMBL6680961 | 0.80 | EPHX2 (0.61) | EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1539683-A2 | PHENOL DERIVATIVES AND THEIR USE AS ROTAMASE INHIBITORS | Jerini AG (DE) | 2005-06-15 | — | — | EP | claimed |
| WO-2004026815-A2 | PHENOL DERIVATIVES AND THEIR USE AS ROTAMASE INHIBITORS | JERINI AG (DE) | 2004-04-01 | — | — | WO | claimed |