Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALCRL | Q16602 | 19/20 | 0.48 |
| ▸ | RAMP1 | O60894 | 4/20 | 0.48 |
| ▸ | CALCA | P06881 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 10/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6225345 | 1.00 | CALCRL (0.48) | CALCRLRAMP1CALCACYP3A4 | |
| SCHEMBL6227894 | 0.91 | CALCRL (0.46) | CALCRLRAMP1CALCACYP3A4 | |
| SCHEMBL3278369 | 0.91 | CALCRL (0.58) | CALCRLRAMP1CALCACYP3A4 | |
| SCHEMBL3278619 | 0.91 | CALCRL (0.58) | CALCRLRAMP1CALCACYP3A4 | |
| SCHEMBL6224472 | 0.90 | CALCRL (0.41) | CALCRLRAMP1CALCACYP3A4 | |
| SCHEMBL3879129 | 0.88 | CALCRL (0.50) | CALCRLRAMP1CYP3A4 | |
| SCHEMBL3885446 | 0.88 | CALCRL (0.50) | CALCRLRAMP1CYP3A4 | |
| SCHEMBL6227753 | 0.88 | CALCRL (0.47) | CALCRLRAMP1CALCACYP3A4 | |
| SCHEMBL6225688 | 0.87 | CALCRL (0.47) | CALCRLRAMP1CALCACYP3A4 | |
| SCHEMBL6225497 | 0.87 | CALCRL (0.56) | CALCRLCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1558601-A1 | SELECTED CGRP ANTAGONISTS, METHOD FOR PRODUCTION AND USE THEREOF AS MEDICAMENT | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2005-08-03 | — | — | EP | claimed |
| WO-2004037811-A1 | SELECTED CGRP ANTAGONISTS, METHOD FOR PRODUCTION AND USE THEREOF AS MEDICAMENT | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2004-05-06 | — | — | WO | claimed |
| EP-1558601-A1 | SELECTED CGRP ANTAGONISTS, METHOD FOR PRODUCTION AND USE THEREOF AS MEDICAMENT | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2005-08-03 | — | — | EP | disclosed |
| WO-2004037811-A1 | SELECTED CGRP ANTAGONISTS, METHOD FOR PRODUCTION AND USE THEREOF AS MEDICAMENT | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2004-05-06 | — | — | WO | disclosed |