SCHEMBL6225949

SCHEMBL6225949

N[C@@H](c1ccccc1)[C@@H](NS(=O)(=O)c1ccc2ccccc2c1)c1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC1A3 P43003 1/20 0.58
SLC1A2 P43004 1/20 0.58
SLC1A1 P43005 1/20 0.58
L3MBTL1 Q9Y468 1/20 0.50
MEN1 O00255 3/20 0.48
KMT2A Q03164 3/20 0.48
CYP1A2 P05177 3/20 0.47
CYP3A4 P08684 3/20 0.47
CYP2C9 P11712 3/20 0.47
TSHR P16473 2/20 0.47
CYP2C19 P33261 2/20 0.47
MAPT P10636 2/20 0.47
PKM P14618 1/20 0.47
F2 P00734 3/20 0.47
PRSS1 P07477 2/20 0.47
PRSS2 P07478 2/20 0.47
PRSS3 P35030 2/20 0.47
LMNA P02545 3/20 0.46
LARS1 Q9P2J5 1/20 0.45
KAT6A Q92794 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31702343 1.00 SLC1A3 (0.58) SLC1A3SLC1A2SLC1A1L3MBTL1MEN1
SCHEMBL811050 1.00 SLC1A3 (0.58) SLC1A3SLC1A2SLC1A1L3MBTL1MEN1
SCHEMBL27621675 1.00 SLC1A3 (0.58) SLC1A3SLC1A2SLC1A1L3MBTL1MEN1
SCHEMBL6227872 1.00 SLC1A3 (0.58) SLC1A3SLC1A2SLC1A1L3MBTL1MEN1
SCHEMBL27602983 1.00 SLC1A3 (0.58) SLC1A3SLC1A2SLC1A1L3MBTL1MEN1
Benzene SCHEMBL4853957 0.99 SLC1A3 (0.56) SLC1A3SLC1A2SLC1A1L3MBTL1MEN1
Benzene SCHEMBL4855262 0.99 SLC1A3 (0.56) SLC1A3SLC1A2SLC1A1L3MBTL1MEN1
Hexamethylbenzene SCHEMBL4865465 0.94 SLC1A3 (0.52) SLC1A3SLC1A2SLC1A1L3MBTL1MEN1
Hexamethylbenzene SCHEMBL4865260 0.94 SLC1A3 (0.52) SLC1A3SLC1A2SLC1A1L3MBTL1MEN1
SCHEMBL4865237 0.92 SLC1A3 (0.51) SLC1A3SLC1A2SLC1A1L3MBTL1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4201926-A1 NOVEL INTERMEDIATE, PREPARATION METHOD FOR SAME, AND APPLICATIONS THEREOF Sichuan University (CN) 2023-06-28 EP disclosed
WO-2022127321-A1 NOVEL INTERMEDIATE, PREPARATION METHOD FOR SAME, AND APPLICATIONS THEREOF 四川大学 2022-06-23 WO disclosed
EP-1512678-A1 Process for preparing optically active nitro compounds and cyano compounds Kanto Kagaku Kabushiki Kaisha (JP) 2005-03-09 EP disclosed